Non-Cochrane · intervention · PM40655937
Antimicrobial effect of silver diamine fluoride (SDF) in arresting dentine caries of permanent teeth: A Systematic review.
Alowid Albandri Mohammed, Hebbal Mamata, Almufarji Fatimah Salim, et al. · F1000Research · 2024 · PubMed · doi:10.12688/f1000research.158864.1
Full textEvery question was extracted from the full text, figures and supplements by two independent LLM extractors, disagreements adjudicated. Rows cite where in the review the value comes from.
Questions
0
current version
GRADE rated
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No studies
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Included studies
9
linked below
Review question
| Element | Planned (methods) | Found (results) |
|---|---|---|
| Population | Permanent teeth with dentinal caries (enamel/cementum caries and primary or bovine teeth excluded) | Permanent teeth with dentine caries; specimens were mainly dentine blocks/slices from extracted human third molars, plus in-situ and in-vivo human carious lesions (n=9 studies) |
| Intervention | Silver diamine fluoride (SDF) | SDF, predominantly 38% (also 31.3% and 12% noted; combinations SDF+NaF and SDF+KI) (n=9) |
| Comparison | Other antimicrobial agents: sodium fluoride varnish, potassium iodide, silver nitrate, chlorhexidine, plasma jet, deionized water | Deionized/distilled water or sterile saline; sodium fluoride; silver nitrate; chlorhexidine; potassium iodide; cold atmospheric plasma (n=9) |
| Outcomes | Antimicrobial effect and caries arrest in dentinal caries | Antimicrobial effect (viable bacteria/CFU/biofilm reduction, inhibition zones); dentine demineralization/lesion depth; collagen degradation (hydroxyproline); surface microhardness and mineral content |
| Study designs | In vitro and in vivo studies published in English (January 2010-September 2022) | In vitro (n=7); in situ (n=1); in vivo (n=1) |
| Timing | Not specified | In vitro/in situ exposure and incubation times ranged from 6 hours to 21 days |
Search date: September 2022. Databases: Google Scholar; Cochrane Library; PubMed
Questions and results
No questions were extracted from this review.
Included primary studies 9
Open as a trial list| Study | Also included by | Outcomes it informs here | Trial PICO | Results |
|---|---|---|---|---|
| Abdullah 2020 The antibacterial efficacy of silver diamine fluoride (SDF) is not modulated by potassium iodide (KI) supplements: A study on in-situ… PMID:33141868 | this review only | not stated | not extracted yet | not extracted yet |
| Chu 2011 Effects of silver diamine fluoride on dentine carious lesions induced by <i>Streptococcus mutans</i> and <i>Actinomyces naeslundii</i>… DOI:10.1111/j.1365-263x.2011.01149.x | this review only | not stated | not extracted yet | not extracted yet |
| Hertel 2018 Antibacterial Efficacy of Plasma Jet, Dielectric Barrier Discharge, Chlorhexidine, and Silver Diamine Fluoride Varnishes in Caries Lesions DOI:10.1615/plasmamed.2018024767 | this review only | not stated | not extracted yet | not extracted yet |
| Karched 2019 <i>In vivo</i> antimicrobial activity of silver diammine fluoride on carious lesions in dentin DOI:10.2334/josnusd.17-0366 | this review only | not stated | not extracted yet | not extracted yet |
| Mei 2013 (demineralisation/collagen) Inhibitory effect of silver diamine fluoride on dentine demineralisation and collagen degradation DOI:10.1016/j.jdent.2013.06.009 | this review only | not stated | not extracted yet | not extracted yet |
| Mei 2013 (dual-species biofilm) Caries arresting effect of silver diamine fluoride on dentine carious lesion with S. mutans and L. acidophilus dual-species cariogenic… PMID:23722131 | this review only | not stated | not extracted yet | not extracted yet |
| Mei 2013 (multi-species biofilm) Antibacterial effects of silver diamine fluoride on multi-species cariogenic biofilm on caries. PMID:23442825 | this review only | not stated | not extracted yet | not extracted yet |
| Yu 2018 Caries-arresting effects of silver diamine fluoride and sodium fluoride on dentine caries lesions DOI:10.1016/j.jdent.2018.08.007 | this review only | not stated | not extracted yet | not extracted yet |
| Zhao 2017 Arresting simulated dentine caries with adjunctive application of silver nitrate solution and sodium fluoride varnish: an in vitro study. PMID:28332192 | this review only | not stated | not extracted yet | not extracted yet |