Cochrane · systematic review · CD015031

Pars plana vitrectomy with internal limiting membrane flap versus pars plana vitrectomy with conventional internal limiting membrane peeling for large macular hole

Ghoraba, H, Rittiphairoj, T, Akhavanrezayat, A, et al. · Cochrane Database of Systematic Reviews · 2023 · Cochrane Library

Eyes and VisionAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
4
No studies
2
Included studies
NR
No studies 2 · 33.3%Ungraded 0 · 0%Very low 1 · 16.7%Low 1 · 16.7%Moderate 2 · 33.3%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Summary of findings

Population: people with large macular hole
6 questions
OutcomeEffectEvidenceStatus / GRADE
Mean change in BCVA from baseline
no estimate extractedNRNo studies
Mean postoperative BCVA (lower is better)
no estimate extractedNRVery low
Downgraded: risk of bias, imprecision, indirectness
Overall closure of macular hole at end of
RR 1.1 [1.02, 1.18]NRModerate
Downgraded: risk of bias
Speed of visual acuity improvement
no estimate extractedNRNo studies
Type 1 macular hole closure at end of
RR 1.31 [1.03, 1.66]NRModerate
Downgraded: risk of bias
Postoperative retinal detachment at end of
no estimate extractedNRLow
Downgraded: imprecision