Cochrane · systematic review · CD014936

Smoking cessation for secondary prevention of cardiovascular disease

Wu, AD, Lindson, N, Hartmann-Boyce, J, et al. · Cochrane Database of Systematic Reviews · 2022 · Cochrane Library

Tobacco AddictionAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
2
current version
GRADE rated
2
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 1 · 50%Moderate 1 · 50%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Smoking cessation compared to continuous smoking for prevention of secondary cardiovascular disease events

Population: people with coronary heart diease
2 questions
OutcomeEffectEvidenceStatus / GRADE
Death from cardiovascular disease at 19 months to 126 months
Smoking cessation vs continuous smoking
HR 0.61 [0.49, 0.75]18 studies · 17982 participantsModerate
Downgraded: risk of bias, inconsistency
Major adverse cardiovascular events (MACE) at 19 months to 110 months
Smoking cessation vs continuous smoking
HR 0.57 [0.45, 0.71]15 studies · 20521 participantsLow
Downgraded: risk of bias, inconsistency, publication bias