Cochrane · systematic review · CD013847
Prognosis of adults and children following a first unprovoked seizure
Neligan, A, Adan, G, Nevitt, SJ, et al. · Cochrane Database of Systematic Reviews · 2023 · Cochrane Library
EpilepsyAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
9
current version
GRADE rated
9
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 9 · 100%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Seizure recurrence and mortality at 6 months
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mixed (adults and children) | no estimate extracted | 27 studies · 7111 participants | Moderate Downgraded: risk of bias, inconsistency |
Adults | no estimate extracted | 7 studies · 1914 participants | Moderate Downgraded: risk of bias, inconsistency |
Children | no estimate extracted | 14 studies · 2232 participants | Moderate Downgraded: risk of bias, inconsistency |
Seizure recurrence and mortality at 12 months
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mixed (adults and children) | no estimate extracted | 34 studies · 6843 participants | Moderate Downgraded: risk of bias, inconsistency |
Adults | no estimate extracted | 9 studies · 2468 participants | Moderate Downgraded: risk of bias, inconsistency |
Children | no estimate extracted | 16 studies · 2313 participants | Moderate Downgraded: risk of bias, inconsistency |
Seizure recurrence and mortality at 24 months
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mixed (adults and children) | no estimate extracted | 27 studies · 6908 participants | Moderate Downgraded: risk of bias, inconsistency |
Adults | no estimate extracted | 9 studies · 2043 participants | Moderate Downgraded: risk of bias, inconsistency |
Children | no estimate extracted | 12 studies · 2172 participants | Moderate Downgraded: risk of bias, inconsistency |