Cochrane · systematic review · CD013259
Prehabilitation versus no prehabilitation to improve functional capacity, reduce postoperative complications and improve quality of life in colorectal cancer surgery
Molenaar, CJL, van Rooijen, SJ, Fokkenrood, HJP, et al. · Cochrane Database of Systematic Reviews · 2023 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
8
current version
GRADE rated
4
No studies
2
Included studies
NR
No studies 2 · 25%Ungraded 2 · 25%Very low 1 · 12.5%Low 2 · 25%Moderate 1 · 12.5%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Current version onlyPrehabilitation compared to no prehabilitation in adult patients undergoing surgery for colorectal cancer
Population: adult patients undergoing surgery for colorectal cancer
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Functional capacity 4 weeks postoperatively Prehabilitation vs no prehabilitation | no estimate extracted | 2 studies · 131 participants | Low Downgraded: risk of bias |
Functional capacity 8 weeks postoperatively Prehabilitation vs no prehabilitation | no estimate extracted | 2 studies · 140 participants | Very low Downgraded: risk of bias |
Complications within 30 days postoperatively Prehabilitation vs no prehabilitation | RR 0.95 [0.7, 1.29] | 3 studies · 250 participants | Low Downgraded: risk of bias |
Health‐related quality of life Prehabilitation vs no prehabilitation | no estimate extracted | 2 studies · 182 participants | Ungraded |
Functional capacity pre‐surgery Prehabilitation vs no prehabilitation | no estimate extracted | 3 studies · 225 participants | Moderate Downgraded: risk of bias |
Length of hospital stay Prehabilitation vs no prehabilitation | no estimate extracted | 3 studies · 250 participants | Ungraded |
Mortality Prehabilitation vs no prehabilitation | no estimate extracted | NR | No studies |
Safety of the programme (dropout, SAE) Prehabilitation vs no prehabilitation | no estimate extracted | NR | No studies |
Prehabilitation compared to no prehabilitation in adult patients undergoing surgery for colorectal cancer
Population: adult patients undergoing surgery for colorectal cancer
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Functional capacity 4 weeks postoperatively Prehabilitation vs no prehabilitation | no estimate extracted | 2 studies · 131 participants | Low Downgraded: risk of bias |
Functional capacity 8 weeks postoperatively Prehabilitation vs no prehabilitation | no estimate extracted | 2 studies · 140 participants | Very low Downgraded: risk of bias |
Complications within 30 days postoperatively Prehabilitation vs no prehabilitation | RR 0.95 [0.7, 1.29] | 3 studies · 250 participants | Low Downgraded: risk of bias |
Health‐related quality of life Prehabilitation vs no prehabilitation | no estimate extracted | 2 studies · 182 participants | Ungraded |
Functional capacity pre‐surgery Prehabilitation vs no prehabilitation | no estimate extracted | 3 studies · 225 participants | Moderate Downgraded: risk of bias |
Length of hospital stay Prehabilitation vs no prehabilitation | no estimate extracted | 3 studies · 250 participants | Ungraded |
Mortality Prehabilitation vs no prehabilitation | no estimate extracted | NR | No studies |
Safety of the programme (dropout, SAE) Prehabilitation vs no prehabilitation | no estimate extracted | NR | No studies |