Cochrane · systematic review · CD013224
Protons versus photons for the treatment of chordoma
El Sayed, I, Trifiletti, DM, Lehrer, EJ, et al. · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library
Gynaecological, Neuro-oncology and Orphan CancerAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
4
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 4 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Protons compared to photons for the treatment of chordoma
Population: adults with chordoma
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Local control ( Protons vs photons | HR 5.34 [0.66, 43.43] | 39 participants | Very low Downgraded: risk of bias, imprecision |
Mortality ( Protons vs photons | HR 0.44 [0.13, 1.57] | 65 participants | Very low Downgraded: risk of bias, imprecision |
Recurrence ( Protons vs photons | HR 0.34 [0.1, 1.17] | 81 participants | Very low Downgraded: risk of bias, imprecision |
Treatment‐related toxicity Protons vs photons | RR 1.28 [0.17, 9.86] | 1 study · 33 participants | Very low Downgraded: risk of bias, imprecision |