Cochrane · systematic review · CD013117

Ivermectin treatment in humans for reducing malaria transmission

de Souza, DK, Thomas, R, Bradley, J, et al. · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library

Infectious DiseasesAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
2
current version
GRADE rated
2
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 2 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Ivermectin versus control in humans to reduce malaria transmission

Population: adults and children living in malaria‐endemic areas
2 questions
OutcomeEffectEvidenceStatus / GRADE
Incidence of clinical malaria
Ivermectin vs control
no estimate extracted590 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Adverse events
Ivermectin vs control
RR 1.63 [1, 2.67]2712 participantsVery low
Downgraded: risk of bias, imprecision, indirectness