Cochrane · systematic review · CD013080

Accuracy of measures for antiretroviral adherence in people living with HIV

Smith, R, Villanueva, G, Probyn, K, et al. · Cochrane Database of Systematic Reviews · 2022 · Cochrane Library

Infectious DiseasesAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 6 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Summary of findings table 1: all index tests

6 questions
OutcomeEffectEvidenceStatus / GRADE
Index test: self‐report All participants ≥ 95% adherence threshold Any viral load threshold
no estimate extracted25 studies · 9211 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, indirectness
Index test: VAS All participants ≥ 95% adherence threshold Any viral load threshold
no estimate extracted11 studies · 4235 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, indirectness
Index test: tablet counts All participants ≥ 95% adherence threshold Any viral load threshold
no estimate extracted12 studies · 3466 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, indirectness
Index test: pharmacy records or secondary database All participants ≥95% adherence threshold Any viral load threshold
no estimate extracted6 studies · 2254 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, indirectness
Index test: electronic monitoring All participants ≥ 95% adherence threshold Any viral load threshold
no estimate extracted3 studies · 186 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, indirectness
Index test: composite measure All participants Different thresholds* Any viral load threshold
no estimate extracted9 studies · 1513 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, indirectness