Cochrane · systematic review · CD012913

Urgent‐start peritoneal dialysis versus conventional‐start peritoneal dialysis for people with chronic kidney disease

Htay, H, Johnson, DW, Craig, JC, et al. · Cochrane Database of Systematic Reviews · 2020 · Cochrane Library

Kidney and TransplantAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
30
current version
GRADE rated
18
No studies
12
Included studies
NR
No studies 12 · 40%Ungraded 0 · 0%Very low 17 · 56.7%Low 1 · 3.3%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Summary of findings of randomised controlled trials

Population: people with CKD
10 questions
OutcomeEffectEvidenceStatus / GRADE
Dialysate leak
RR 3.9 [1.56, 9.78]1 study · 122 participantsLow
Downgraded: imprecision, indirectness
Catheter blockage
no estimate extractedNRNo studies
Catheter malposition
no estimate extractedNRNo studies
PD dialysate flow problem
no estimate extractedNRNo studies
Exit‐site infection
no estimate extractedNRNo studies
Exit‐site bleeding
RR 0.7 [0.03, 16.81]1 study · 122 participantsVery low
Downgraded: imprecision, indirectness
Tunnel tract infection
no estimate extractedNRNo studies
Peritonitis
no estimate extractedNRNo studies
Catheter readjustment
no estimate extractedNRNo studies
Technique survival
RR 1.09 [1, 1.2]1 study · 122 participantsVery low
Downgraded: imprecision, indirectness

Summary of findings of non‐randomised study interventions: cohort studies

Population: people with CKD
10 questions
OutcomeEffectEvidenceStatus / GRADE
Dialysate leak
RR 2.06 [0.8, 5.28]1322 participantsVery low
Downgraded: imprecision
Catheter blockage
RR 1.33 [0.4, 4.43]4 studies · 1214 participantsVery low
Downgraded: imprecision
Catheter malposition
RR 1.63 [0.8, 3.32]6 studies · 1353 participantsVery low
Downgraded: imprecision
PD dialysate flow problem
RR 1.44 [0.34, 6.14]3 studies · 937 participantsVery low
Downgraded: imprecision
Exit‐site infection
RR 1.43 [0.24, 8.61]2 studies · 337 participantsVery low
Downgraded: imprecision
Exit‐site bleeding
RR 1.58 [0.07, 35.32]1 study · 27 participantsVery low
Downgraded: imprecision
Tunnel tract infection
no estimate extractedNRNo studies
Peritonitis
RR 1 [0.68, 1.46]7 studies · 1497 participantsVery low
Downgraded: imprecision
Catheter readjustment
RR 1.27 [0.4, 4.02]2 studies · 739 participantsVery low
Downgraded: imprecision
Technique survival
RR 0.9 [0.76, 1.07]8 studies · 1668 participantsVery low
Downgraded: imprecision

Summary of findings of non‐randomised study interventions: case‐control studies

Population: people with CKD
10 questions
OutcomeEffectEvidenceStatus / GRADE
Dialysate leak
RR 7.41 [1.27, 43.36]2 studies · 160 participantsVery low
Downgraded: imprecision
Catheter blockage
RR 1.89 [0.58, 6.13]2 studies · 160 participantsVery low
Downgraded: imprecision
Catheter malposition
RR 3 [0.64, 13.96]1 study · 104 participantsVery low
Downgraded: imprecision
PD dialysate flow problem
no estimate extractedNRNo studies
Exit‐site infection
RR 1.2 [0.41, 3.5]1 study · 104 participantsVery low
Downgraded: imprecision
Exit‐site bleeding
no estimate extractedNRNo studies
Tunnel tract infection
no estimate extractedNRNo studies
Peritonitis
RR 1.09 [0.12, 9.51]2 studies · 160 participantsVery low
Downgraded: imprecision
Catheter readjustment
no estimate extractedNRNo studies
Technique survival
RR 0.92 [0.79, 1.06]2 studies · 160 participantsVery low
Downgraded: imprecision