Cochrane · systematic review · CD011862
Antecolic versus retrocolic reconstruction after partial pancreaticoduodenectomy
Hüttner, FJ, Klotz, R, Ulrich, A, et al. · Cochrane Database of Systematic Reviews · 2022 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
8
current version
GRADE rated
8
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 1 · 12.5%Low 6 · 75%Moderate 0 · 0%High 1 · 12.5%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Current version onlySummary of findings
Population: adults with any pancreatic diagnosis leading to an indication for elective (classical, pylorus‐preserving, pylorus‐resecting) partial pancreatoduodenectomy
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Delayed gastric emptying (all definitions) | OR 0.67 [0.41, 1.09] | 8 studies · 818 participants | Low Downgraded: risk of bias |
Mortality (within 30 days or 'in‐hospital') | no estimate extracted | 8 studies · 818 participants | High |
Pancreatic fistula | OR 1.01 [0.73, 1.4] | 8 studies · 818 participants | Low Downgraded: risk of bias |
Postoperative haemorrhage | OR 0.87 [0.47, 1.59] | 6 studies · 742 participants | Low Downgraded: risk of bias |
Intra‐abdominal fluid collection, abscess | OR 1.11 [0.71, 1.74] | 7 studies · 788 participants | Low Downgraded: risk of bias |
Reoperations | OR 0.68 [0.34, 1.36] | 5 studies · 682 participants | Low Downgraded: risk of bias |
Length of postoperative hospital stay (days) | no estimate extracted | 8 studies · 818 participants | Low Downgraded: risk of bias |
Quality of life (EQ‐5D, EORTC QLQ‐C30 and PAN26, GIQLI at 2, 4 and 12 weeks after surgery) | no estimate extracted | 1 study · 73 participants | Very low Downgraded: risk of bias |
Comparison
Population: Adults with any pancreatic diagnosis leading to an indication for elective (classical, pylorus‐preserving, pylorus‐resecting) partial pancreatoduodenectomy
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Delayed gastric emptying (all definitions) | OR 0.6 [0.31, 1.18] | 6 studies · 576 participants | Low Downgraded: risk of bias |
Mortality | no estimate extracted | 6 studies · 576 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency |
Pancreatic fistula | OR 0.98 [0.65, 1.47] | 6 studies · 576 participants | Low Downgraded: risk of bias |
Postoperative haemorrhage | OR 0.79 [0.38, 1.65] | 5 studies · 530 participants | Low Downgraded: risk of bias |
Intra‐abdominal fluid collection, abscess | OR 0.93 [0.52, 1.67] | 6 studies · 576 participants | Low Downgraded: risk of bias |
Reoperations | OR 0.59 [0.27, 1.31] | 4 studies · 470 participants | Low Downgraded: risk of bias, imprecision, inconsistency |
Length of postoperative hospital stay | no estimate extracted | 6 studies · 576 participants | Low Downgraded: risk of bias |
Quality of life | no estimate extracted | 1 study · 73 participants | Low Downgraded: risk of bias, imprecision, inconsistency |