Cochrane · systematic review · CD011745

Antihypertensive pharmacotherapy for prevention of sudden cardiac death in hypertensive individuals

Taverny, G, Mimouni, Y, LeDigarcher, A, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library

HypertensionAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
3
current version
GRADE rated
3
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 3 · 100%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Antihypertensive pharmacotherapy versus control for prevention of sudden cardiac death in hypertensive individuals

Population: people with hypertension (defined as baseline systolic resting blood pressure ≥ 140 mmHg and/or resting diastolic blood pressure ≥ 90 mmHg)
3 questions
OutcomeEffectEvidenceStatus / GRADE
Sudden cardiac death (
Antihypertensive pharmacotherapy vs control
RR 0.96 [0.81, 1.15]15 studies · 39908 participantsModerate
Downgraded: imprecision
Non‐fatal myocardial infarction (
Antihypertensive pharmacotherapy vs control
RR 0.85 [0.74, 0.98]15 studies · 39908 participantsModerate
Downgraded: imprecision
Fatal myocardial infarction (
Antihypertensive pharmacotherapy vs control
RR 0.75 [0.62, 0.9]15 studies · 39908 participantsModerate
Downgraded: imprecision