Cochrane · systematic review · CD011670
Early versus delayed appendicectomy for appendiceal phlegmon or abscess
Zhou, S, Cheng, Y, Cheng, N, et al. · Cochrane Database of Systematic Reviews · 2024 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
14
current version
GRADE rated
9
No studies
5
Included studies
NR
No studies 5 · 35.7%Ungraded 0 · 0%Very low 9 · 64.3%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Current version onlyEarly versus delayed open or laparoscopic appendicectomy for appendiceal phlegmon
Population: paediatric and adult participants with appendiceal phlegmon
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Overall morbidity Median Early vs delayed open or laparoscopic appendicectomy | RR 0.74 [0.19, 2.86] | 3 studies · 146 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Wound infection Median Early vs delayed open or laparoscopic appendicectomy | RR 0.99 [0.48, 2.02] | 7 studies · 788 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Abdominal abscess Median Early vs delayed open or laparoscopic appendicectomy | RR 0.26 [0.08, 0.8] | 4 studies · 626 participants | Very low Downgraded: risk of bias, imprecision |
Faecal fistula Median Early vs delayed open or laparoscopic appendicectomy | RR 1.75 [0.36, 8.49] | 5 studies · 388 participants | Very low Downgraded: risk of bias, imprecision |
Mortality Median Early vs delayed open or laparoscopic appendicectomy | no estimate extracted | 7 studies · 788 participants | Very low Downgraded: risk of bias, imprecision |
Total length of hospital stay (days) Early vs delayed open or laparoscopic appendicectomy | no estimate extracted | 5 studies · 680 participants | Very low Downgraded: risk of bias, inconsistency |
Time away from normal activities (days) Median Early vs delayed open or laparoscopic appendicectomy | MD 5 [1.52, 8.48] | 1 study · 40 participants | Very low Downgraded: risk of bias, imprecision |
Early versus delayed laparoscopic appendicectomy for appendiceal abscess
Population: paediatric participants with appendiceal abscess
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Overall morbidity Early vs delayed laparoscopic appendicectomy | no estimate extracted | NR | No studies |
Wound infection Early vs delayed laparoscopic appendicectomy | no estimate extracted | NR | No studies |
Abdominal abscess Early vs delayed laparoscopic appendicectomy | no estimate extracted | NR | No studies |
Faecal fistula Early vs delayed laparoscopic appendicectomy | no estimate extracted | NR | No studies |
Mortality Early vs delayed laparoscopic appendicectomy | no estimate extracted | 1 study · 40 participants | Very low Downgraded: risk of bias, imprecision |
Total length of hospital stay (days) Early vs delayed laparoscopic appendicectomy | no estimate extracted | 1 study · 40 participants | Very low Downgraded: risk of bias, imprecision |
Time away from normal activities (days) Early vs delayed laparoscopic appendicectomy | no estimate extracted | NR | No studies |
Early versus delayed open appendicectomy for appendiceal phlegmon
Population: paediatric and adult patients with appendiceal phlegmon
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Overall morbidity Median Early vs delayed open appendicectomy | RR 13 [0.78, 216.39] | 1 study · 40 participants | Very low Downgraded: risk of bias, imprecision |
Wound infection Median Early vs delayed open appendicectomy | RR 9 [0.52, 156.91] | 1 study · 40 participants | Very low Downgraded: risk of bias, imprecision |
Faecal fistula Median Early vs delayed open appendicectomy | RR 3 [0.13, 69.52] | 1 study · 40 participants | Very low Downgraded: risk of bias, imprecision |
Mortality Median Early vs delayed open appendicectomy | no estimate extracted | 1 study · 40 participants | Low Downgraded: imprecision |
Total length of hospital stay (days) Early vs delayed open appendicectomy | MD 6.7 [2.76, 10.64] | 1 study · 40 participants | Very low Downgraded: risk of bias, imprecision |
Time away from normal activities (days) Median Early vs delayed open appendicectomy | MD 5 [1.52, 8.48] | 1 study · 40 participants | Very low Downgraded: risk of bias, imprecision |
Quality of life Median Early vs delayed open appendicectomy | no estimate extracted | NR | No studies |
Pain (days) Early vs delayed open appendicectomy | no estimate extracted | NR | No studies |
Early versus delayed laparoscopic appendicectomy for appendiceal abscess
Population: paediatric participants with appendiceal abscess
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Overall morbidity Early vs delayed laparoscopic appendicectomy | no estimate extracted | NR | No studies |
Wound infection Early vs delayed laparoscopic appendicectomy | no estimate extracted | NR | No studies |
Faecal fistula Early vs delayed laparoscopic appendicectomy | no estimate extracted | NR | No studies |
Mortality Early vs delayed laparoscopic appendicectomy | no estimate extracted | 1 study · 40 participants | Very low Downgraded: imprecision |
Total length of hospital stay (days) Early vs delayed laparoscopic appendicectomy | no estimate extracted | 1 study · 40 participants | Very low Downgraded: risk of bias, imprecision |
Time away from normal activities (days) Early vs delayed laparoscopic appendicectomy | no estimate extracted | NR | No studies |
Quality of life (Pediatric Quality of Life Scale‐Version 4.0, a scale of 0 to 100 with higher values indicating better quality of life) Early vs delayed laparoscopic appendicectomy | MD 12.4 [9.78, 15.02] | 1 study · 40 participants | Very low Downgraded: risk of bias, imprecision |
Pain (days) Early vs delayed laparoscopic appendicectomy | no estimate extracted | NR | No studies |