Cochrane · systematic review · CD011499
Renal denervation for resistant hypertension
Pisano, A, Iannone, LF, Leo, A, et al. · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
10
current version
GRADE rated
10
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 4 · 40%Moderate 6 · 60%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Current version onlySummary of findings
Population: people with resistant hypertension
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Myocardial infarction | no estimate extracted | 4 studies · 742 participants | Low Downgraded: imprecision |
Ischaemic stroke | no estimate extracted | 5 studies · 892 participants | Low Downgraded: imprecision |
Unstable angina | no estimate extracted | 3 studies · 270 participants | Low Downgraded: imprecision |
Hospitalisation | no estimate extracted | 3 studies · 743 participants | Low Downgraded: imprecision |
Systolic 24‐hour ABPM (mmHg) | no estimate extracted | 9 studies · 1045 participants | Moderate Downgraded: imprecision |
Diastolic 24‐hour ABPM (mmHg) | no estimate extracted | 8 studies · 1004 participants | Moderate Downgraded: imprecision |
Systolic office BP (mmHg) | no estimate extracted | 9 studies · 1090 participants | Moderate Downgraded: imprecision |
Diastolic office BP (mmHg) | no estimate extracted | 8 studies · 1049 participants | Moderate Downgraded: imprecision |
eGFR or creatinine clearance (mL/min/1.73m²) | no estimate extracted | 6 studies · 822 participants | Moderate Downgraded: imprecision |
Serum creatinine (mg/dL) | no estimate extracted | 5 studies · 721 participants | Moderate Downgraded: imprecision |
Comparison
Population: people with resistant hypertension
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
myocardial infarction | no estimate extracted | 4 studies · 742 participants | Low Downgraded: imprecision |
ischaemic stroke | no estimate extracted | 4 studies · 823 participants | Low Downgraded: imprecision |
unstable angina | no estimate extracted | 2 studies · 201 participants | Low Downgraded: imprecision |
systolic 24‐hour ABPM (mmHg) | no estimate extracted | 5 studies · 797 participants | Moderate Downgraded: imprecision |
diastolic 24‐hour ABPM (mmHg) | no estimate extracted | 4 studies · 756 participants | Moderate Downgraded: imprecision |
systolic office BP (mmHg) | no estimate extracted | 6 studies · 886 participants | Moderate Downgraded: imprecision |
diastolic office BP (mmHg) | no estimate extracted | 5 studies · 845 participants | Moderate Downgraded: imprecision |
eGFR or creatinine clearance (mL/min/1.73m²) | no estimate extracted | 4 studies · 837 participants | Moderate Downgraded: imprecision |