Cochrane · systematic review · CD011487
Antiviral agents for infectious mononucleosis (glandular fever)
De Paor, M, O'Brien, K, Fahey, T, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library
Acute Respiratory InfectionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 7 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Antivirals compared with placebo/no treatment for infectious mononucleosis (glandular fever)
Population: patients diagnosed with clinical and laboratory‐confirmed diagnosis of infectious mononucleosis (glandular fever)
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Time to clinical recovery doctor judgement Antivirals vs placebo/no treatment | no estimate extracted | 2 studies · 87 participants | Very low Downgraded: imprecision |
Time to clinical recovery patient judgement Antivirals vs placebo/no treatment | no estimate extracted | 2 studies · 87 participants | Very low Downgraded: imprecision |
Adverse events and side effects Antivirals vs placebo/no treatment | no estimate extracted | 5 studies · 248 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Duration of lymphadenopathy Antivirals vs placebo/no treatment | no estimate extracted | 2 studies · 61 participants | Very low Downgraded: imprecision |
Development of complications of Infectious mononucleosis Antivirals vs placebo/no treatment | no estimate extracted | 3 studies · 108 participants | Very low Downgraded: imprecision |
Viral shedding Antivirals vs placebo/no treatment | no estimate extracted | 6 studies · 268 participants | Very low Downgraded: imprecision |
Days missing from school / work Antivirals vs placebo/no treatment | no estimate extracted | 2 studies · 87 participants | Very low Downgraded: imprecision |