Cochrane · systematic review · CD011478

Type II or type III radical hysterectomy compared to chemoradiotherapy as a primary intervention for stage IB2 cervical cancer

Nama, V, Angelopoulos, G, Twigg, J, et al. · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library

SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
4
current version
GRADE rated
2
No studies
2
Included studies
NR
No studies 2 · 50%Ungraded 0 · 0%Very low 2 · 50%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Chemoradiotherapy versus radical surgery for stage IB2 cervical cancers

Population: women (18 years and older) diagnosed with stage IB2 cervical cancer
4 questions
OutcomeEffectEvidenceStatus / GRADE
Overall survival (5‐year)
Chemoradiotherapy vs radical surgery
no estimate extractedNRVery low
Downgraded: risk of bias
Progression‐free survival (5‐year)
Chemoradiotherapy vs radical surgery
no estimate extractedNRNo studies
Recurrence
Chemoradiotherapy vs radical surgery
OR 2.26 [1.24, 4.14]1 study · 215 participantsVery low
Downgraded: risk of bias
Adverse events: lymphoedema
Chemoradiotherapy vs radical surgery
no estimate extractedNRNo studies