Cochrane · systematic review · CD011420

Lateral flow urine lipoarabinomannan assay for detecting active tuberculosis in people living with HIV

Bjerrum, S, Schiller, I, Dendukuri, N, et al. · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library

Infectious Diseases2 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
10
current version
GRADE rated
0
No studies
10
Included studies
NR
No studies 10 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Current version only

LF‐LAM for symptomatic participants

CD011420.PUB3 (current) · 5 questions
OutcomeEffectEvidenceStatus / GRADE
Test result
no estimate extractedNRNo studies
True positives
no estimate extractedNRNo studies
False negatives
no estimate extractedNRNo studies
True negatives
no estimate extractedNRNo studies
False positives
no estimate extractedNRNo studies

LF‐LAM for unselected participants

CD011420.PUB3 (current) · 5 questions
OutcomeEffectEvidenceStatus / GRADE
Test result
no estimate extractedNRNo studies
True positives
no estimate extractedNRNo studies
False negatives
no estimate extractedNRNo studies
True negatives
no estimate extractedNRNo studies
False positives
no estimate extractedNRNo studies

LF‐LAM (grade 2) for TB diagnosis

Population: HIV‐positive adults with symptoms of TB Index test: LF‐LAM (grade 2) Role: a replacement test or additional test along with sputum smear microscopy or sputum Xpert® MTB/RIF Reference standard: microbiological (mainly mycobacterial culture) Studies: cross‐sectional
CD011420.PUB2 · 3 questions
OutcomeEffectEvidenceStatus / GRADE
Test result
no estimate extractedNRNo studies
Inconclusive
no estimate extractedNRNo studies
Complications
no estimate extractedNRNo studies

LF‐LAM (grade 2) for TB screening

Population: HIV‐positive adults regardless of signs and symptoms of TB Index test: LF‐LAM (grade 2) Role: a replacement test or additional test along with sputum smear microscopy or sputum Xpert® MTB/RIF Reference standard: microbiological (mainly mycobacterial culture) Studies: cross‐sectional
CD011420.PUB2 · 3 questions
OutcomeEffectEvidenceStatus / GRADE
Test result
no estimate extractedNRNo studies
Inconclusive
no estimate extractedNRNo studies
Complications
no estimate extractedNRNo studies