Cochrane · systematic review · CD011202
Use of biochemical tests of placental function for improving pregnancy outcome
Heazell, AEP, Whitworth, M, Duley, L, et al. · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library
Pregnancy and ChildbirthAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 3 · 42.9%Low 4 · 57.1%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Test of placental function compared with standard care for improving pregnancy outcome
Population: women in the third trimester of pregnancy
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Death of a baby (stillbirth or neonatal death) report of perinatal death Test of placental function vs standard care | RR 0.88 [0.36, 2.13] | 2 studies · 740 participants | Very low Downgraded: risk of bias |
Stillbirth report of stillbirth Test of placental function vs standard care | RR 0.56 [0.16, 1.88] | 2 studies · 740 participants | Very low Downgraded: risk of bias, imprecision |
Neonatal death report of neonatal death Test of placental function vs standard care | RR 1.62 [0.39, 6.74] | 2 studies · 740 participants | Very low Downgraded: risk of bias, imprecision |
Small‐for‐gestational age (below 10th centile on customised birthweight chart or as defined by trialists) birthweight centile chart Test of placental function vs standard care | RR 0.44 [0.16, 1.19] | 1 study · 118 participants | Low Downgraded: imprecision |
Preterm birth (before 37 weeks' gestation) reported gestation at birth Test of placental function vs standard care | RR 2.9 [0.12, 69.81] | 1 study · 118 participants | Low Downgraded: imprecision |
Elective delivery (induction of labour or non‐labour caesarean section) report of mode of delivery Test of placental function vs standard care | RR 0.98 [0.84, 1.14] | 2 studies · 740 participants | Low Downgraded: risk of bias, imprecision |
Caesarean section report of mode of delivery Test of placental function vs standard care | RR 0.48 [0.15, 1.52] | 1 study · 118 participants | Low Downgraded: imprecision |