Cochrane · systematic review · CD010973

Pharmacological interventions for recurrent abdominal pain in childhood

Martin, AE, Newlove‐Delgado, TV, Abbott, RA, et al. · Cochrane Database of Systematic Reviews · 2017 · Cochrane Library

SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
4
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 3 · 75%Low 1 · 25%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Antispasmodics compared to placebo for recurrent abdominal pain

Population: school‐aged children (5 to 18 years of age) with recurrent abdominal pain
4 questions
OutcomeEffectEvidenceStatus / GRADE
Pain duration (mean pain duration, assessed at 4 weeks)
Antispasmodics vs placebo
no estimate extracted1 study · 120 participantsVery low
Downgraded: risk of bias
Pain improvement (clinician judged, assessed at 2 weeks)
Antispasmodics vs placebo
OR 3.33 [0.93, 12.01]1 study · 42 participantsVery low
Downgraded: risk of bias
Pain frequency (episodes of pain in 4 weeks, assessed after 4 weeks)
Antispasmodics vs placebo
MD 11.3 [2.4, 20.1]1 study · 132 participantsVery low
Downgraded: risk of bias
Pain improvement (self reported response to treatment, assessed at 4 weeks)
Antispasmodics vs placebo
OR 1.6 [0.7, 3.4]1 study · 115 participantsLow