Cochrane · systematic review · CD010681
Adjuvant chemotherapy for advanced endometrial cancer
Galaal, K, Al Moundhri, M, Bryant, A, et al. · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library
Gynaecological, Neuro-oncology and Orphan CancerAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
5
current version
GRADE rated
5
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 5 · 100%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Summary of findings
Population: women with stage III or IV endometrial cancer after primary cytoreductive surgery
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
5‐ year OS | HR 0.75 [0.57, 0.99] | 2 studies · 620 participants | Moderate |
5‐year PFS | HR 0.74 [0.59, 0.92] | 2 studies · 620 participants | Moderate |
5‐year OS (stage III) | HR 0.76 [0.57, 1.02] | 2 studies · 514 participants | Moderate |
5‐year PFS (stage III) | HR 0.81 [0.63, 1.05] | 2 studies · 514 participants | Moderate |
Summary of findings
Population: women with advanced (stage III/IV) endometrial cancer after surgery and radiotherapy
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
PFS (stage III/IV) Median | HR 0.9 [0.69, 1.17] | 1 study · 552 participants | Moderate |