Cochrane · systematic review · CD010666
Micronutrient supplementation for children with HIV infection
Irlam, JH, Siegfried, N, Visser, ME, et al. · Cochrane Database of Systematic Reviews · 2013 · Cochrane Library
HIV/AIDSAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
19
current version
GRADE rated
19
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 5 · 26.3%Moderate 14 · 73.7%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Vitamin A for children with HIV infection
Population: Children with HIV infection
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
All‐cause mortality Death reports | RR 0.55 [0.37, 0.82] | 3 studies · 262 participants | Moderate |
Child growth at 12 months ‐ Wasting Anthropometric measurements at monthly clinic visits | RR 0.25 [0.06, 1.05] | 1 study · 41 participants | Low |
Child growth at 12 months ‐ Stunting Anthropometric measurements at monthly clinic visits | RR 0.67 [0.34, 1.32] | 1 study · 29 participants | Low |
Vitamin D for children with HIV infection
Population: Children with HIV infection
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
CD4 counts at 12 months | no estimate extracted | 1 study · 56 participants | Low |
Viral load at 12 months | no estimate extracted | 1 study · 56 participants | Low |
Zinc for children with HIV infection
Population: Children with HIV infection
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Viral load at 9 months | no estimate extracted | 1 study · 85 participants | Moderate |
Mortality at 9 months Hospital records and verbal autopsies | RR 0.31 [0.07, 1.42] | 1 study · 96 participants | Low |
CD4 % at 9 months | no estimate extracted | 1 study · 85 participants | Moderate |
All clinic visits ‐ watery diarrhoea | RR 0.51 [0.34, 0.76] | 1 study · 854 participants | Moderate |
All clinic visits ‐ URI | RR 0.75 [0.55, 1.03] | 1 study · 854 participants | Moderate |
All clinic visits ‐ pneumonia | RR 0.89 [0.76, 1.04] | 1 study · 854 participants | Moderate |
All clinic visits ‐ ear infection | RR 0.78 [0.55, 1.11] | 1 study · 854 participants | Moderate |
Multiple micronutrients for children with HIV infection
Population: Children with HIV infection
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mortality at 12 months | RR 0.88 [0.52, 1.49] | 1 study · 847 participants | Moderate |
CD4 count | no estimate extracted | 1 study · 399 participants | Moderate |
Duration of hospitalisation ‐ All admissions | no estimate extracted | 1 study · 106 participants | Moderate |
Change in appetite at 6 months | no estimate extracted | 1 study · 99 participants | Moderate |
Anthropometric Z scores ‐ WAZ at 6 months | no estimate extracted | 1 study · 99 participants | Moderate |
Anthropometric Z scores ‐ HAZ at 6 months | no estimate extracted | 1 study · 99 participants | Moderate |
Anthropometric Z scores ‐ WHZ at 6 months | no estimate extracted | 1 study · 99 participants | Moderate |