Cochrane · systematic review · CD010571

Pancreatic duct guidewire placement for biliary cannulation for the prevention of post‐endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis

Tse, F, Yuan, Y, Bukhari, M, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library

GutAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 7 · 100%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Pancreatic duct guidewire (PGW) or double guidewire technique (DGT) compared to other endoscopic techniques for the prevention of post‐endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis

Population: people with biliary cannulation for the prevention of post‐ERCP pancreatitis
7 questions
OutcomeEffectEvidenceStatus / GRADE
Post‐ERCP pancreatitis
Pancreatic duct guidewire (PGW) or double guidewire technique (DGT) vs other endoscopic techniques
RR 1.98 [1.14, 3.42]7 studies · 577 participantsLow
Downgraded: risk of bias, imprecision, publication bias
CBD cannulation success with the randomised technique (before the use of rescue techniques)
Pancreatic duct guidewire (PGW) or double guidewire technique (DGT) vs other endoscopic techniques
RR 1.04 [0.87, 1.24]7 studies · 577 participantsLow
Downgraded: risk of bias
Overall cannulation success
Pancreatic duct guidewire (PGW) or double guidewire technique (DGT) vs other endoscopic techniques
RR 1.04 [0.91, 1.18]7 studies · 577 participantsLow
Downgraded: risk of bias
Post‐ERCP bleeding
Pancreatic duct guidewire (PGW) or double guidewire technique (DGT) vs other endoscopic techniques
RR 0.48 [0.13, 1.79]6 studies · 513 participantsLow
Downgraded: risk of bias, imprecision
Post‐ERCP perforation
Pancreatic duct guidewire (PGW) or double guidewire technique (DGT) vs other endoscopic techniques
RR 0.94 [0.06, 14.78]6 studies · 513 participantsLow
Downgraded: risk of bias, imprecision
Post‐ERCP cholangitis
Pancreatic duct guidewire (PGW) or double guidewire technique (DGT) vs other endoscopic techniques
RR 2.71 [0.79, 9.35]4 studies · 373 participantsLow
Downgraded: risk of bias, imprecision
Mortality
Pancreatic duct guidewire (PGW) or double guidewire technique (DGT) vs other endoscopic techniques
RR 0.31 [0.01, 7.58]2 studies · 258 participantsLow
Downgraded: risk of bias, imprecision