Cochrane · systematic review · CD010473

Continuous positive airway pressure (CPAP) for acute bronchiolitis in children

Jat, KR, Dsouza, JM, Mathew, JL · Cochrane Database of Systematic Reviews · 2022 · Cochrane Library

Acute Respiratory Infections3 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
4
current version
GRADE rated
2
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 2 · 50%Very low 0 · 0%Low 2 · 50%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Current version only

Continuous positive airway pressure (CPAP) compared to supportive treatment for acute bronchiolitis in children

Population: children with acute bronchiolitis
CD010473.PUB4 (current) · 4 questions
OutcomeEffectEvidenceStatus / GRADE
Proportion of children requiring mechanical ventilation
Continuous positive airway pressure (CPAP) vs supportive treatment
no estimate extracted3 studies · 122 participantsLow
Downgraded: risk of bias, imprecision
Time to recovery(hours)
Continuous positive airway pressure (CPAP) vs supportive treatment
no estimate extracted0 studies · 0 participantsUngraded
Mean change in respiratory rate (breaths/min)
Continuous positive airway pressure (CPAP) vs supportive treatment
no estimate extracted2 studies · 91 participantsLow
Downgraded: risk of bias
Adverse effects
Continuous positive airway pressure (CPAP) vs supportive treatment
no estimate extracted1 study · 72 participantsUngraded

Continuous positive airway pressure (CPAP) compared to supportive treatment for acute bronchiolitis in children

Population: children with acute bronchiolitis
CD010473.PUB3 · 3 questions
OutcomeEffectEvidenceStatus / GRADE
Proportion of children requiring mechanical ventilation observation
Continuous positive airway pressure (CPAP) vs supportive treatment
RR 0.69 [0.14, 3.36]3 studies · 122 participantsLow
Downgraded: risk of bias, imprecision
Time to recovery (hours)
Continuous positive airway pressure (CPAP) vs supportive treatment
no estimate extracted0 studies · 0 participantsUngraded
Change in respiratory rate
Continuous positive airway pressure (CPAP) vs supportive treatment
no estimate extracted2 studies · 91 participantsLow
Downgraded: risk of bias

Continuous positive airway pressure (CPAP) compared to standard treatment for acute bronchiolitis in children

Population: children with acute bronchiolitis
CD010473.PUB2 · 4 questions
OutcomeEffectEvidenceStatus / GRADE
Proportion of patients requiring mechanical ventilation Observation
Continuous positive airway pressure (CPAP) vs standard treatment
RR 0.19 [0.01, 3.63]2 studies · 50 participantsLow
Downgraded: imprecision
Change in partial pressure of carbon dioxide from start to end of intervention (mmHg) Arterial blood gas analysis
Continuous positive airway pressure (CPAP) vs standard treatment
no estimate extracted2 studies · 50 participantsLow
Downgraded: imprecision
Duration of hospital stay (days) Observation
Continuous positive airway pressure (CPAP) vs standard treatment
no estimate extracted2 studies · 50 participantsLow
Downgraded: imprecision
Time to recovery Hours
Continuous positive airway pressure (CPAP) vs standard treatment
no estimate extracted0 studies · 3 participantsUngraded