Cochrane · systematic review · CD010217

Transurethral radiofrequency collagen denaturation for the treatment of women with urinary incontinence

Kang, D, Han, J, Neuberger, MM, et al. · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library

IncontinenceAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
5
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 2 · 28.6%Very low 0 · 0%Low 5 · 71.4%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Transurethral radiofrequency collagen denaturation compared with no treatment/sham treatment for women with UI

Population: women with symptomatic UI
7 questions
OutcomeEffectEvidenceStatus / GRADE
Participant‐reported measures: number of women reporting UI symptoms
Transurethral radiofrequency collagen denaturation vs no treatment/sham treatment
no estimate extracted0 studies · 0 participantsUngraded
Serious adverse events
Transurethral radiofrequency collagen denaturation vs no treatment/sham treatment
no estimate extracted1 study · 173 participantsLow
Downgraded: risk of bias
Disease‐specific quality of life: number of women with an I‐QOL score improvement ≥ 10 points at 12 months
Transurethral radiofrequency collagen denaturation vs no treatment/sham treatment
RR 1.11 [0.77, 1.62]1 study · 142 participantsLow
Downgraded: risk of bias
Repeat continence surgery: number of women undergoing repeat continence surgery
Transurethral radiofrequency collagen denaturation vs no treatment/sham treatment
no estimate extracted0 studies · 0 participantsUngraded
Other adverse event: pain/dysuria: dysuria
Transurethral radiofrequency collagen denaturation vs no treatment/sham treatment
RR 5.73 [0.75, 43.7]1 study · 173 participantsLow
Downgraded: risk of bias
Other adverse event: (new) detrusor overactivity: overactive bladder symptoms
Transurethral radiofrequency collagen denaturation vs no treatment/sham treatment
RR 1.36 [0.63, 2.93]1 study · 173 participantsLow
Downgraded: risk of bias
Other adverse event: urinary tract infection
Transurethral radiofrequency collagen denaturation vs no treatment/sham treatment
RR 0.95 [0.24, 3.86]1 study · 173 participantsLow
Downgraded: risk of bias