Cochrane · systematic review · CD010168

Abdominal drainage to prevent intra‐peritoneal abscess after appendectomy for complicated appendicitis

Li, Z, Li, Z, Zhao, L, et al. · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library

Colorectal3 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
8
current version
GRADE rated
5
No studies
3
Included studies
NR
No studies 3 · 37.5%Ungraded 0 · 0%Very low 2 · 25%Low 3 · 37.5%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Current version only

Drainage compared to no drainage after open appendectomy for complicated appendicitis

Population: people undergoing emergency open appendectomy for complicated appendicitis
CD010168.PUB4 (current) · 8 questions
OutcomeEffectEvidenceStatus / GRADE
Intraperitoneal abscess
Drainage vs no drainage after open appendectomy
RR 1.23 [0.47, 3.21]5 studies · 453 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Wound infection
Drainage vs no drainage after open appendectomy
RR 2.01 [0.88, 4.56]5 studies · 478 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Morbidity
Drainage vs no drainage after open appendectomy
RR 6.67 [2.13, 20.87]1 study · 90 participantsLow
Downgraded: risk of bias, imprecision
Mortality
Drainage vs no drainage after open appendectomy
Peto OR 4.88 [1.18, 20.09]4 studies · 363 participantsLow
Downgraded: risk of bias, imprecision
Hospital stay (days)
Drainage vs no drainage after open appendectomy
MD 2.173 studies · 298 participantsLow
Downgraded: risk of bias, imprecision
Hospital cost
Drainage vs no drainage after open appendectomy
no estimate extractedNRNo studies
Pain
Drainage vs no drainage after open appendectomy
no estimate extractedNRNo studies
Quality of life
Drainage vs no drainage after open appendectomy
no estimate extractedNRNo studies

Drainage compared to no drainage for complicated appendicitis

Population: people undergoing emergency open appendectomy for complicated appendicitis
CD010168.PUB3 · 8 questions
OutcomeEffectEvidenceStatus / GRADE
Intra‐peritoneal abscess
Drainage vs no drainage
RR 1.23 [0.47, 3.21]5 studies · 453 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Wound infection
Drainage vs no drainage
RR 2.01 [0.88, 4.56]5 studies · 478 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Morbidity
Drainage vs no drainage
RR 6.67 [2.13, 20.87]1 study · 90 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Mortality
Drainage vs no drainage
Peto OR 4.88 [1.18, 20.09]4 studies · 363 participantsModerate
Downgraded: risk of bias, imprecision, inconsistency
Hospital stay (days)
Drainage vs no drainage
MD 2.173 studies · 298 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Hospital cost
Drainage vs no drainage
no estimate extractedNRNo studies
Pain
Drainage vs no drainage
no estimate extractedNRNo studies
Quality of life
Drainage vs no drainage
no estimate extractedNRNo studies

Abdominal drainage to prevent intra‐peritoneal abscess after open appendectomy for complicated appendicitis

Population: patients undergoing emergency open appendectomy for complicated appendicitis
CD010168.PUB2 · 5 questions
OutcomeEffectEvidenceStatus / GRADE
Intra‐peritoneal abscess
RR 1.23 [0.47, 3.21]5 studies · 453 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, publication bias
Wound infection
RR 1.67 [0.75, 3.74]4 studies · 410 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, publication bias
Morbidity
RR 6.67 [2.13, 20.87]1 study · 90 participantsVery low
Downgraded: risk of bias, imprecision, publication bias
Mortality
Peto OR 4.88 [1.18, 20.09]4 studies · 363 participantsVery low
Downgraded: risk of bias, imprecision, publication bias
Hospital stay
no estimate extracted2 studies · 230 participantsVery low
Downgraded: risk of bias, imprecision, publication bias