Cochrane · systematic review · CD010019
Outpatient versus inpatient treatment for acute pulmonary embolism
Yoo, HHB, Nunes-Nogueira, VS, Fortes Villas Boas, PJ, et al. · Cochrane Database of Systematic Reviews · 2022 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 7 · 100%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Current version onlyOutpatient versus inpatient treatment for acute pulmonary embolism
Population: people with low‐risk acute pulmonary embolism
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Short‐term all‐cause mortality Outpatient vs inpatient treatment | no estimate extracted | 2 studies · 453 participants | Low Downgraded: imprecision, publication bias |
Short‐term all‐cause mortality Outpatient vs inpatient treatment | RR 0.33 [0.01, 7.98] | 2 studies · 453 participants | Low Downgraded: imprecision, publication bias |
Long‐term all‐cause mortality Outpatient vs inpatient treatment | RR 0.98 [0.06, 15.58] | 2 studies · 451 participants | Low Downgraded: imprecision, publication bias |
Major bleeding Outpatient vs inpatient treatment | RR 4.91 [0.24, 101.57] | 2 studies · 445 participants | Low Downgraded: imprecision, publication bias |
Major bleeding Outpatient vs inpatient treatment | RR 6.88 [0.36, 132.14] | 2 studies · 445 participants | Low Downgraded: imprecision, publication bias |
Minor bleeding Outpatient vs inpatient treatment | RR 1.08 [0.07, 16.79] | 1 study · 106 participants | Low Downgraded: imprecision, publication bias |
Recurrent PE Outpatient vs inpatient treatment | RR 2.95 | 2 studies · 445 participants | Low Downgraded: imprecision, publication bias |
Outpatient compared with inpatient treatment for acute pulmonary embolism
Population: people with low‐risk acute pulmonary embolism
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Short‐term all‐cause mortality Outpatient vs inpatient treatment | RR 0.33 [0.01, 7.98] | 2 studies · 453 participants | Low Downgraded: imprecision, publication bias |
Long‐term all‐cause mortality Outpatient vs inpatient treatment | RR 0.98 [0.06, 15.58] | 2 studies · 4514 participants | Low Downgraded: imprecision, publication bias |
Major bleeding Outpatient vs inpatient treatment | RR 4.91 [0.24, 101.57] | 2 studies · 445 participants | Low Downgraded: imprecision, publication bias |
Major bleeding Outpatient vs inpatient treatment | RR 6.88 [0.36, 132.14] | 2 studies · 445 participants | Low Downgraded: imprecision, publication bias |
Minor bleeding Outpatient vs inpatient treatment | RR 1.08 [0.07, 16.79] | 1 study · 106 participants | Low Downgraded: imprecision, publication bias |
Recurrent PE Outpatient vs inpatient treatment | RR 2.95 | 2 studies · 445 participants | Low Downgraded: imprecision, publication bias |
Outpatient compared with inpatient treatment for acute pulmonary embolism
Population: people with acute pulmonary embolism
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Short‐term all‐cause mortality Outpatient vs inpatient treatment | RR 0.33 [0.01, 7.98] | 1 study · 339 participants | Low Downgraded: imprecision, publication bias |
Long‐term all‐cause mortality Outpatient vs inpatient treatment | RR 0.98 [0.06, 15.58] | 1 study · 339 participants | Low Downgraded: imprecision, publication bias |