Cochrane · systematic review · CD009987
Decentralising HIV treatment in lower‐ and middle‐income countries
Kredo, T, Ford, N, Adeniyi, FB, et al. · Cochrane Database of Systematic Reviews · 2013 · Cochrane Library
HIV/AIDSAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
9
current version
GRADE rated
9
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 2 · 22.2%Low 2 · 22.2%Moderate 5 · 55.6%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Antiretroviral therapy initiated in a hospital, maintained at a health centre for HIV infected patients
Population: HIV infected patients
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Death or lost to care | RR 0.46 [0.29, 0.71] | 4 studies · 39090 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Lost to care | RR 0.55 [0.45, 0.69] | 4 studies · 39090 participants | Low Downgraded: imprecision, inconsistency, indirectness |
Death | RR 0.34 [0.13, 0.87] | 4 studies · 39090 participants | Low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Antiretroviral therapy started and maintained in a health centre for HIV infected patients
Population: HIV infected patients
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Death or lost to care | RR 0.7 [0.47, 1.02] | 4 studies · 56360 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Lost to care | RR 0.3 [0.17, 0.54] | 4 studies · 56360 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Death | RR 1.1 [0.63, 1.92] | 4 studies · 55099 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Decentralisation from the facility to the community for antiretroviral maintenance therapy for HIV‐infected patients on antiretroviral therapy
Population: HIV‐infected patients
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Death or lost to care | RR 0.95 [0.62, 1.46] | 2 studies · 709 participants | Moderate Downgraded: imprecision, indirectness |
Lost to care | RR 0.81 [0.3, 2.21] | 2 studies · 709 participants | Moderate Downgraded: imprecision, indirectness |
Death | RR 1.03 [0.64, 1.65] | 2 studies · 709 participants | Moderate Downgraded: imprecision, indirectness |