Cochrane · systematic review · CD009834
Antibiotics for persistent cough or wheeze following acute bronchiolitis in children
McCallum, GB, Plumb, EJ, Morris, PS, et al. · Cochrane Database of Systematic Reviews · 2017 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
3
current version
GRADE rated
3
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 3 · 100%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Current version onlyAntibiotics compared with placebo or no treatment for persistent respiratory symptoms following acute bronchiolitis
Population: children < 24 months with persistent respiratory symptoms following acute bronchiolitis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Number of participants who were not cured at Antibiotics vs placebo or no treatment | OR 0.69 [0.37, 1.28] | 2 studies · 249 participants | Low Downgraded: risk of bias, imprecision |
Number of participants rehospitalised for a respiratory illness Antibiotics vs placebo or no treatment | OR 1.19 [0.67, 2.12] | 2 studies · 240 participants | Low Downgraded: risk of bias, imprecision |
Proportion of participants with recurrent wheeze Antibiotics vs placebo or no treatment | OR 0.47 [0.06, 3.95] | 2 studies · 240 participants | Low Downgraded: risk of bias, imprecision |
Antibiotics compared with placebo or no treatment for persistent respiratory symptoms following acute bronchiolitis
Population: children < 24 months with ongoing symptoms (cough/wheeze) post‐acute bronchiolitis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Proportion of participants who were not cured at Antibiotics vs placebo or no treatment | no estimate extracted | 1 study · 30 participants | Low Downgraded: imprecision |
Proportion of participants who were readmitted within 6 months Antibiotics vs placebo or no treatment | no estimate extracted | 1 study · 21 participants | Low Downgraded: imprecision |
Adverse events Antibiotics vs placebo or no treatment | no estimate extracted | 1 study · 30 participants | Ungraded |