Cochrane · systematic review · CD009780

Implementation of treatment guidelines for specialist mental health care

Bighelli, I, Ostuzzi, G, Girlanda, F, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library

Schizophrenia2 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
15
current version
GRADE rated
9
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 6 · 40%Very low 6 · 40%Low 3 · 20%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Current version only

Active education + Support for implementation compared with Routine care or Passive dissemination for participants with schizophrenia and related psychosis

Population: participants with schizophrenia and related psychosis
CD009780.PUB3 (current) · 7 questions
OutcomeEffectEvidenceStatus / GRADE
Process outcome, Practitioner Impact 1. Polypharmacy at
Active education + Support for implementation vs Routine care or Passive dissemination
RR 0.97 [0.75, 1.25]2 studies · 310 participantsVery low
Downgraded: risk of bias, imprecision
Process outcome, Practitioner Impact: 2. Not screened for cardiovascular risk, Framingham score (corrected for design effect)
Active education + Support for implementation vs Routine care or Passive dissemination
RR 0.71 [0.48, 1.03]1 study · 38 participantsVery low
Downgraded: risk of bias, imprecision
Patient outcome: Global state: average score (PANSS total, high = poor)
Active education + Support for implementation vs Routine care or Passive dissemination
no estimate extracted1 study · 59 participantsVery low
Downgraded: risk of bias, imprecision
Patient outcome: satisfaction with care: average score (ZUF8, high = better satisfaction)
Active education + Support for implementation vs Routine care or Passive dissemination
no estimate extracted1 study · 46 participantsVery low
Downgraded: risk of bias, imprecision
Patient outcome: treatment adherence: not adherent at
Active education + Support for implementation vs Routine care or Passive dissemination
RR 0.9 [0.44, 1.85]1 study · 52 participantsVery low
Downgraded: risk of bias, imprecision
Patient outcome: drug attitude: average score (DAI, high = positive attitude)
Active education + Support for implementation vs Routine care or Passive dissemination
no estimate extracted1 study · 32 participantsVery low
Downgraded: risk of bias, imprecision
Patient outcome: quality of life
Active education + Support for implementation vs Routine care or Passive dissemination
no estimate extracted0 studies · 0 participantsUngraded

Re‐written guideline text compared to original guideline text for patients with schizophrenia and related psychosis

Population: patients with schizophrenia and related psychosis
CD009780.PUB3 (current) · 8 questions
OutcomeEffectEvidenceStatus / GRADE
Process outcome, Practitioner Impact 3. Staff not trained (as suggested by the guideline)
Re‐written guideline text vs original guideline text
RR 1.03 [0.87, 1.21]1 study · 68 participantsLow
Downgraded: imprecision
Process outcome, Practitioner Impact 4. Staff not supervised (as suggested by the guideline)
Re‐written guideline text vs original guideline text
RR 0.86 [0.64, 1.17]1 study · 68 participantsLow
Downgraded: imprecision
Process outcome, Practitioner Impact 5. Staff did not provide psychological interventions (as suggested by the guideline)
Re‐written guideline text vs original guideline text
RR 0.86 [0.62, 1.18]1 study · 68 participantsLow
Downgraded: imprecision
Patient outcome: Global state
Re‐written guideline text vs original guideline text
no estimate extracted0 studies · 0 participantsUngraded
Patient outcome: Satisfaction with care
Re‐written guideline text vs original guideline text
no estimate extracted0 studies · 0 participantsUngraded
Patient outcome: Treatment adherence
Re‐written guideline text vs original guideline text
no estimate extracted0 studies · 0 participantsUngraded
Patient outcome: Drug attitude
Re‐written guideline text vs original guideline text
no estimate extracted0 studies · 0 participantsUngraded
Patient outcome: Quality of life
Re‐written guideline text vs original guideline text
no estimate extracted0 studies · 0 participantsUngraded

Active education + Support for implementation compared with Routine care or Passive dissemination for participants with schizophrenia and related psychosis

Population: participants with schizophrenia and related psychosis
CD009780.PUB2 · 7 questions
OutcomeEffectEvidenceStatus / GRADE
Polypharmacy at
Active education + Support for implementation vs Routine care or Passive dissemination
RR 0.97 [0.75, 1.25]310 participantsVery low
Downgraded: risk of bias, imprecision
Not screened for cardiovascular risk factors
Active education + Support for implementation vs Routine care or Passive dissemination
RR 0.71 [0.48, 1.03]38 participantsVery low
Downgraded: risk of bias, imprecision
Global state—PANSS total score
Active education + Support for implementation vs Routine care or Passive dissemination
no estimate extracted59 participantsVery low
Downgraded: risk of bias, imprecision
Satisfaction with care—ZUF8
Active education + Support for implementation vs Routine care or Passive dissemination
no estimate extracted46 participantsVery low
Downgraded: risk of bias, imprecision
Lack of treatment adherence—design effect corrected
Active education + Support for implementation vs Routine care or Passive dissemination
RR 0.9 [0.44, 1.85]52 participantsVery low
Downgraded: risk of bias, imprecision
Drug attitude—DAI
Active education + Support for implementation vs Routine care or Passive dissemination
no estimate extracted32 participantsVery low
Downgraded: risk of bias, imprecision
Quality of life
Active education + Support for implementation vs Routine care or Passive dissemination
no estimate extracted0 studies · 0 participantsUngraded