Cochrane · systematic review · CD009683

Topiramate for essential tremor

Bruno, E, Nicoletti, A, Quattrocchi, G, et al. · Cochrane Database of Systematic Reviews · 2017 · Cochrane Library

Movement DisordersAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
3
current version
GRADE rated
3
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 1 · 33.3%Low 2 · 66.7%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Topiramate for essential tremor

Population: people with essential tremor
3 questions
OutcomeEffectEvidenceStatus / GRADE
Functional disability (
no estimate extracted1 study · 223 participantsVery low
Downgraded: risk of bias, indirectness
Study withdrawal (
RR 1.78 [1.23, 2.6]2 studies · 285 participantsLow
Downgraded: risk of bias
Adverse events (
no estimate extracted1 study · 221 participantsLow
Downgraded: risk of bias