Cochrane · systematic review · CD009648

CHIVA method for the treatment of chronic venous insufficiency

Bellmunt-Montoya, S, Escribano, JM, Pantoja Bustillos, PE, et al. · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library

Vascular3 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
5
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 1 · 20%Very low 0 · 0%Low 4 · 80%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Current version only

CHIVA compared to stripping for the treatment of chronic venous insufficiency

Population: people with CVI (CEAP 2–6)
CD009648.PUB4 (current) · 5 questions
OutcomeEffectEvidenceStatus / GRADE
Recurrence of varicose veins
CHIVA vs stripping
RR 0.74 [0.46, 1.2]5 studies · 966 participantsLow
Downgraded: risk of bias, inconsistency
Side effects – bruises
CHIVA vs stripping
no estimate extracted2 studies · 646 participantsUngraded
Side effects – limb infection
CHIVA vs stripping
RR 0.83 [0.33, 2.1]3 studies · 746 participantsLow
Downgraded: risk of bias, imprecision
Side effects – superficial vein thrombosis
CHIVA vs stripping
RR 1.05 [0.51, 2.17]4 studies · 846 participantsLow
Downgraded: risk of bias, imprecision
Side effects – nerve injury
CHIVA vs stripping
RR 0.14 [0.02, 0.98]4 studies · 846 participantsLow
Downgraded: risk of bias, imprecision, inconsistency

Comparison

Population: adults with varicose veins
CD009648.PUB3 · 5 questions
OutcomeEffectEvidenceStatus / GRADE
Recurrence of varicose veins (
RR 0.63 [0.51, 0.78]3 studies · 721 participantsModerate
Side effects ‐ bruises (
RR 0.63 [0.53, 0.76]1 study · 501 participantsModerate
Downgraded: imprecision
Side effects ‐ limb infection (
RR 1.33 [0.38, 4.66]1 study · 501 participantsLow
Downgraded: imprecision
Side effects ‐ superficial vein thrombosis (
RR 2.23 [0.6, 8.33]2 studies · 601 participantsLow
Side effects ‐ nerve damage (
RR 0.05 [0.01, 0.38]2 studies · 601 participantsModerate

Comparison

Population: adults with varicose veins
CD009648.PUB2 · 5 questions
OutcomeEffectEvidenceStatus / GRADE
Recurrence of varicose veins (
RR 0.63 [0.51, 0.78]3 studies · 721 participantsModerate
Side effects ‐ bruises (
RR 0.63 [0.53, 0.76]1 study · 501 participantsModerate
Downgraded: imprecision
Side effects ‐ limb infection (
RR 1.33 [0.38, 4.66]1 study · 501 participantsLow
Downgraded: imprecision
Side effects ‐ superficial vein thrombosis (
RR 2.23 [0.6, 8.33]2 studies · 601 participantsLow
Downgraded: imprecision
Side effects ‐ nerve damage (
RR 0.05 [0.01, 0.38]2 studies · 601 participantsModerate
Downgraded: imprecision