Cochrane · systematic review · CD009531

Collaborative care approaches for people with severe mental illness

Reilly, S, Hobson-Merrett, C, Gibbons, B, et al. · Cochrane Database of Systematic Reviews · 2024 · Cochrane Library

Schizophrenia2 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
5
No studies
2
Included studies
NR
No studies 2 · 28.6%Ungraded 0 · 0%Very low 2 · 28.6%Low 3 · 42.9%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Current version only

Summary of findings table ‐ Collaborative care compared to usual care for severe mental illness

Population: severe mental illness
CD009531.PUB3 (current) · 7 questions
OutcomeEffectEvidenceStatus / GRADE
Quality of life: average change in mental health component (proxy for binary quality of life)
Summary of findings table ‐ Collaborative care vs usual care
no estimate extracted3 studies · 227 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, indirectness
Mental state: clinically important change (binary)
Summary of findings table ‐ Collaborative care vs usual care
RR 0.99 [0.77, 1.28]1 study · 253 participantsLow
Downgraded: imprecision, indirectness
Psychiatric hospital admissions
Summary of findings table ‐ Collaborative care vs usual care
RR 5.15 [0.67, 39.57]1 study · 253 participantsLow
Downgraded: imprecision, indirectness
Quality of life: average change in physical health component (proxy for physical health)
Summary of findings table ‐ Collaborative care vs usual care
no estimate extracted3 studies · 237 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Disability (proxy for social functioning)
Summary of findings table ‐ Collaborative care vs usual care
RR 1.38 [0.97, 1.95]1 study · 253 participantsLow
Downgraded: imprecision, indirectness
Personal recovery ‐ not reported
Summary of findings table ‐ Collaborative care vs usual care
no estimate extractedNRNo studies
Experience of care/satisfaction ‐ not reported
Summary of findings table ‐ Collaborative care vs usual care
no estimate extractedNRNo studies

Collaborative care versus standard care for people with severe mental illness

Population: patients with severe mental illness
CD009531.PUB2 · 7 questions
OutcomeEffectEvidenceStatus / GRADE
Psychiatric admissions ‐ number of participants admitted to hospital VA National Patient Care Database and Pharmacy Benefits Management Package.
Collaborative care vs standard care
RR 0.75 [0.57, 0.99]1 study · 306 participantsLow
Downgraded: risk of bias, indirectness
Other non psychiatric admissions ‐ Number of participants admitted to hospital VA National Patient Care Database and Pharmacy Benefits Management Package.
Collaborative care vs standard care
RR 0.83 [0.65, 1.04]1 study · 306 participantsLow
Downgraded: risk of bias, indirectness
Death ‐ Number of participants that died from suicide
Collaborative care vs standard care
RR 0.34 [0.01, 8.32]1 study · 330 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Death ‐ Number of participants that died from natural causes
Collaborative care vs standard care
RR 1.54 [0.65, 3.66]1 study · 330 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Quality of life ‐ Average endpoint in mental health component (SF‐36) (at 36 months) Scale from: 0 to 100.
Collaborative care vs standard care
no estimate extracted1 study · 306 participantsLow
Downgraded: risk of bias, indirectness
Mental state‐ general Not improved to an important extent
Collaborative care vs standard care
no estimate extracted0 studies · 0 participantsUngraded
Social functioning ‐ general Not improved to an important extent
Collaborative care vs standard care
no estimate extracted0 studies · 0 participantsUngraded