Cochrane · systematic review · CD009471

Inhaled corticosteroids in children with persistent asthma: effects on growth

Zhang, L, Prietsch, SOM, Ducharme, FM · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library

AirwaysAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
3
current version
GRADE rated
3
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 3 · 100%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Comparison

Population: children up to 18 years of age with persistent asthma
3 questions
OutcomeEffectEvidenceStatus / GRADE
Linear growth velocity in first year of treatment (cm/y)
no estimate extracted14 studies · 5717 participantsModerate
Downgraded: risk of bias, inconsistency
Change from baseline in height over first year of treatment (cm)
no estimate extracted15 studies · 3275 participantsModerate
Downgraded: risk of bias, inconsistency
Change in height standard deviation score (SDS) in first year of treatment
no estimate extracted4 studies · 258 participantsModerate
Downgraded: risk of bias, inconsistency