Cochrane · systematic review · CD009446

Topical anti‐inflammatory agents for seborrhoeic dermatitis of the face or scalp

Kastarinen, H, Oksanen, T, Okokon, EO, et al. · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library

SkinAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
5
current version
GRADE rated
5
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 3 · 60%Moderate 2 · 40%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Calcineurin inhibitor compared with steroid for seborrhoeic dermatitis of the scalp or face

Population: people with seborrhoeic dermatitis
1 question
OutcomeEffectEvidenceStatus / GRADE
Total clearance (at 4 weeks or less) Investigator's assessment
Calcineurin inhibitor vs steroid
RR 1.08 [0.88, 1.32]2 studies · 60 participantsLow
Downgraded: risk of bias, imprecision

Steroid compared with azole for seborrhoeic dermatitis of the scalp or face

Population: people with seborrhoeic dermatitis of the scalp or face
1 question
OutcomeEffectEvidenceStatus / GRADE
Total clearance (at 4 weeks or less) Investigator's assessment
Steroid vs azole
RR 1.11 [0.94, 1.32]8 studies · 464 participantsModerate
Downgraded: risk of bias

Strong steroid (class III or IV) compared with mild steroid (class I or II) for seborrhoeic dermatitis of the scalp or face

Population: people with seborrhoeic dermatitis
2 questions
OutcomeEffectEvidenceStatus / GRADE
Total clearance (at 4 weeks or less) Investigator's assessment
Strong steroid (class III or IV) vs mild steroid (class I or II)
RR 0.96 [0.65, 1.4]2 studies · 93 participantsModerate
Downgraded: risk of bias, imprecision
Total clearance (more than 4 weeks) Investigator's assessment
Strong steroid (class III or IV) vs mild steroid (class I or II)
RR 0.79 [0.63, 0.98]1 study · 117 participantsLow
Downgraded: risk of bias, imprecision

Lithium compared with azole for seborrhoeic dermatitis of the scalp or face

Population: people with seborrhoeic dermatitis
1 question
OutcomeEffectEvidenceStatus / GRADE
Total clearance Investigator's assessment
Lithium vs azole
RR 1.79 [1.1, 2.9]1 study · 288 participantsLow
Downgraded: risk of bias, imprecision