Cochrane · systematic review · CD009075
Aerobic physical exercise for adult patients with haematological malignancies
Knips, L, Bergenthal, N, Streckmann, F, et al. · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 2 · 28.6%Low 4 · 57.1%Moderate 1 · 14.3%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Current version onlyPhysical exercise versus no physical exercise for adults with haematological malignancies
Population: Adults with haematological malignancies
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mortality Physical exercise vs no physical exercise | RR 1.1 [0.79, 1.52] | 6 studies · 1172 participants | Low Downgraded: imprecision |
Quality of Life Scale from: ‐1 to 1 with 1 indicating best outcome Physical exercise vs no physical exercise | SMD 0.11 | 8 studies · 1259 participants | Low Downgraded: risk of bias, imprecision, inconsistency |
Physical functioning/QoL Scale from: ‐1 to 1 with 1 indicating best outcome Physical exercise vs no physical exercise | SMD 0.15 | 8 studies · 1329 participants | Low Downgraded: risk of bias, imprecision, inconsistency |
Depression/QoL Scale from: ‐1 to 1 with 1 indicating best outcome Physical exercise vs no physical exercise | SMD 0.19 | 6 studies · 445 participants | Low Downgraded: imprecision |
Anxiety/QoL Scale from: ‐1 to 1 with 1 indicating best outcome Physical exercise vs no physical exercise | SMD 0.03 | 6 studies · 445 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Fatigue Scale from: ‐1 to 1 with 1 indicating best outcome Physical exercise vs no physical exercise | SMD 0.31 | 9 studies · 826 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency |
Serious adverse events Physical exercise vs no physical exercise | RR 1.39 [0.94, 2.06] | 6 studies · 435 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Physical exercise versus no physical exercise for adults with haematological malignancies
Population: Adults with haematological malignancies
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Overall survival not reported Mortality Physical exercise vs no physical exercise | RR 0.93 [0.59, 1.47] | 3 studies · 269 participants | Moderate Downgraded: imprecision |
Quality of Life Scale from: 0 to 1 with 1 indicating best outcome Physical exercise vs no physical exercise | SMD 0.26 [0.03, 0.49] | 3 studies · 291 participants | Low Downgraded: imprecision |
Physical functioning/QoL Scale from: 0 to 1 with 1 indicating best outcome Physical exercise vs no physical exercise | SMD 0.33 [0.13, 0.52] | 4 studies · 422 participants | Moderate Downgraded: risk of bias, imprecision |
Depression/QoL Scale from: 0 to 1 with 1 indicating best outcome Physical exercise vs no physical exercise | SMD 0.25 [0, 0.5] | 3 studies · 249 participants | Low Downgraded: imprecision |
Anxiety/QoL Scale from: 0 to 1 with 1 indicating best outcome Physical exercise vs no physical exercise | no estimate extracted | 3 studies · 249 participants | Low Downgraded: imprecision |
Fatigue Scale from: 0 to 1 with 1 indicating best outcome Physical exercise vs no physical exercise | SMD 0.24 [0.08, 0.4] | 7 studies · 692 participants | Moderate Downgraded: risk of bias, imprecision |
Physical performance Physical exercise vs no physical exercise | no estimate extracted | NR | No studies |
Serious adverse events Physical exercise vs no physical exercise | RR 1.44 [0.96, 2.18] | 3 studies · 266 participants | Low Downgraded: imprecision |
Adverse events Physical exercise vs no physical exercise | RR 7.23 [0.38, 137.5] | 1 study · 122 participants | Low Downgraded: risk of bias, imprecision |