Cochrane · systematic review · CD009058

Cryotherapy for liver metastases

Bala, MM, Riemsma, RP, Wolff, R, et al. · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library

Hepato-Biliary2 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
3
No studies
3
Included studies
NR
No studies 3 · 42.9%Ungraded 1 · 14.3%Very low 0 · 0%Low 3 · 42.9%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Current version only

Cryotherapy for liver metastasis

Population: people with liver metastases
CD009058.PUB3 (current) · 7 questions
OutcomeEffectEvidenceStatus / GRADE
All‐cause mortality
RR 0.88 [0.77, 1.02]1 study · 123 participantsLow
Downgraded: risk of bias, imprecision
Cancer mortality
no estimate extractedNRNo studies
All adverse events and complications
RR 1.151 participantsUngraded
Health‐related quality of life
no estimate extractedNRNo studies
Recurrence of liver metastases Number of participants developing recurrences of liver metastases
RR 0.9 [0.8, 1.01]1 study · 123 participantsLow
Downgraded: risk of bias, imprecision
Time to progression of liver metastases
no estimate extractedNRNo studies
Tumour response measures
3069 participantsLow

Cryotherapy for liver metastasis

Population: patients with liver metastases.
CD009058.PUB2 · 2 questions
OutcomeEffectEvidenceStatus / GRADE
Mortality Participants alive at last
RR 0.88 [0.77, 1.02]1 study · 123 participantsVery low
Downgraded: risk of bias
Recurrence of liver metastases Number of patients developing recurrences of liver metastases.
RR 0.9 [0.8, 1.01]1 study · 123 participantsVery low
Downgraded: risk of bias