Cochrane · systematic review · CD009009
General health checks in adults for reducing morbidity and mortality from disease
Krogsbøll, LT, Jørgensen, KJ, Gøtzsche, PC · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
5
current version
GRADE rated
5
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 2 · 40%High 3 · 60%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Current version onlyGeneral health checks versus usual care
Population: general adult populations (geriatric trials not included)
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Total mortality General health checks vs usual care | RR 1 [0.97, 1.03] | 11 studies · 233298 participants | High |
Cancer mortality General health checks vs usual care | RR 1.01 [0.92, 1.12] | 8 studies · 139290 participants | High |
Cardiovascular mortality General health checks vs usual care | RR 1.05 [0.94, 1.16] | 9 studies · 170227 participants | Moderate Downgraded: inconsistency |
Fatal and non‐fatal ischaemic heart disease General health checks vs usual care | RR 0.98 [0.94, 1.03] | 4 studies · 164881 participants | High |
Fatal and non‐fatal stroke General health checks vs usual care | RR 1.05 [0.95, 1.17] | 3 studies · 107421 participants | Moderate Downgraded: inconsistency |
General health checks for preventing morbidity and mortality from disease
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Total mortality Deaths | RR 0.99 [0.95, 1.03] | 9 studies · 155899 participants | High |
Cardiovascular mortality Deaths from cardiovascular causes | RR 1.03 [0.91, 1.17] | 8 studies · 152435 participants | Moderate |
Cancer mortality Cancer deaths | RR 1.01 [0.92, 1.12] | 8 studies · 139290 participants | High |