Cochrane · systematic review · CD008996
Eplerenone for hypertension
Tam, TSC, Wu, MHY, Masson, SC, et al. · Cochrane Database of Systematic Reviews · 2017 · Cochrane Library
HypertensionAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
4
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 2 · 50%Moderate 2 · 50%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Comparison
Population: adults with primary hypertension
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Effect on systolic blood pressure (mean difference in systolic blood pressure) | no estimate extracted | 5 studies · 1437 participants | Moderate Downgraded: risk of bias |
Effect on diastolic blood pressure (mean difference in diastolic blood pressure) | no estimate extracted | 5 studies · 1437 participants | Moderate Downgraded: risk of bias |
Any adverse event | OR 1.07 [0.82, 1.41] | 3 studies · 1105 participants | Low Downgraded: risk of bias |
Adverse event leading to withdrawal | OR 1.1 [0.47, 2.55] | 3 studies · 1105 participants | Low Downgraded: risk of bias |