Cochrane · systematic review · CD008986
Medication review in hospitalised patients to reduce morbidity and mortality
Bülow, C, Clausen, SS, Lundh, A, et al. · Cochrane Database of Systematic Reviews · 2023 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
4
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 1 · 25%Low 2 · 50%Moderate 1 · 25%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Current version onlyMedication review compared with standard care for hospitalised adult patients
Population: hospitalised adult patients
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mortality (all‐cause) Median Medication review vs standard care | RR 0.96 [0.87, 1.05] | 18 studies · 10108 participants | Low Downgraded: risk of bias, imprecision, indirectness |
Hospital readmission (all‐cause) Median Medication review vs standard care | RR 0.93 [0.89, 0.98] | 17 studies · 9561 participants | Moderate Downgraded: risk of bias, imprecision, indirectness |
Hospital emergency department contacts (all‐cause) Median Medication review vs standard care | RR 0.84 [0.68, 1.03] | 8 studies · 3527 participants | Low Downgraded: risk of bias, imprecision, indirectness |
Health‐related quality of lifeg Median Medication review vs standard care | SMD 0.1 | 4 studies · 392 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Medication review compared with standard care for hospitalised adult patients
Population: hospitalised adult patients
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mortality (all‐cause) Medication review vs standard care | RR 1.02 [0.87, 1.19] | 9 studies · 3218 participants | Low Downgraded: risk of bias, imprecision, indirectness |
Hospital readmission (all‐cause) Medication review vs standard care | RR 0.95 [0.87, 1.04] | 7 studies · 2843 participants | High |
Hospital emergency department contacts (all‐cause) Medication review vs standard care | RR 0.73 [0.52, 1.03] | 4 studies · 1442 participants | Low Downgraded: risk of bias, imprecision, indirectness |
Medication review compared with standard care for hospitalised adult patients
Population: Hospitalised adult patients
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mortality (all‐cause) Medication review vs standard care | RR 0.98 [0.78, 1.23] | 4 studies · 1002 participants | Low Downgraded: risk of bias |
Hospital readmission (all‐cause) Medication review vs standard care | RR 1.01 [0.88, 1.16] | 4 studies · 956 participants | Low Downgraded: risk of bias |
Hospital Emergency Department contacts (all‐cause) Medication review vs standard care | RR 0.64 [0.46, 0.89] | 3 studies · 574 participants | Moderate Downgraded: risk of bias |