Cochrane · systematic review · CD008983

Influenza vaccines in immunosuppressed adults with cancer

Bitterman, R, Eliakim‐Raz, N, Vinograd, I, et al. · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library

Gynaecological, Neuro-oncology and Orphan Cancer2 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
4
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 2 · 50%Low 2 · 50%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Show all 2 versions

Influenza vaccine compared to no vaccine for immunosuppressed adults with cancer

Population: immunosuppressed adults with cancer
3 questions
OutcomeEffectEvidenceStatus / GRADE
All‐cause mortality, solid cancers
Influenza vaccine vs no vaccine
OR 0.88 [0.78, 1]1 study · 1577 participantsVery low
All‐cause mortality, solid and haematological malignancies
Influenza vaccine vs no vaccine
OR 0.42 [0.24, 0.75]1 study · 806 participantsVery low
Downgraded: imprecision
All‐cause mortality, allogeneic BMT
Influenza vaccine vs no vaccine
OR 1.25 [0.43, 3.62]1 study · 78 participantsLow
Downgraded: imprecision

Adjuvanted influenza vaccine compared to non‐adjuvanted influenza vaccine in immunosuppressed adults with cancer

Population: immunosuppressed adults with cancer
1 question
OutcomeEffectEvidenceStatus / GRADE
All‐cause mortality, allogeneic BMT,
Adjuvanted influenza vaccine vs non‐adjuvanted influenza vaccine
RR 0.54 [0.05, 5.73]1 study · 73 participantsLow
Downgraded: imprecision