Cochrane · systematic review · CD008879
Preoperative nutrition therapy in people undergoing gastrointestinal surgery
Sowerbutts, AM, Burden, S, Sremanakova, J, et al. · Cochrane Database of Systematic Reviews · 2024 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
16
current version
GRADE rated
11
No studies
1
Included studies
NR
No studies 1 · 6.3%Ungraded 4 · 25%Very low 6 · 37.5%Low 5 · 31.3%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Current version onlyPreoperative parenteral nutrition compared to usual care or control in people undergoing gastrointestinal surgery
Population: people undergoing gastrointestinal surgery
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Non‐infectious complications Preoperative parenteral nutrition vs usual care or control | RR 0.61 [0.36, 1.02] | 3 studies · 260 participants | Very low Downgraded: risk of bias, indirectness |
Infectious complications Preoperative parenteral nutrition vs usual care or control | RR 0.98 [0.53, 1.8] | 3 studies · 260 participants | Very low Downgraded: risk of bias, inconsistency, indirectness |
Length of hospital stay (days) Preoperative parenteral nutrition vs usual care or control | no estimate extracted | 2 studies · 135 participants | Very low Downgraded: risk of bias, indirectness |
Adverse effects Preoperative parenteral nutrition vs usual care or control | no estimate extracted | 3 studies · 260 participants | Ungraded |
Preoperative enteral nutrition (standard formula) compared to usual care or control in people undergoing gastrointestinal surgery
Population: people undergoing gastrointestinal surgery
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Non‐infectious complications Preoperative enteral nutrition (standard formula) vs usual care or control | no estimate extracted | NR | No studies |
Infectious complications Preoperative enteral nutrition (standard formula) vs usual care or control | RR 0.9 [0.59, 1.38] | 2 studies · 126 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Length of hospital stay (days) Preoperative enteral nutrition (standard formula) vs usual care or control | no estimate extracted | 2 studies · 126 participants | Very low Downgraded: risk of bias, imprecision |
Adverse effects Preoperative enteral nutrition (standard formula) vs usual care or control | no estimate extracted | 1 study · 26 participants | Ungraded |
Immune‐enhancing supplements (oral or enteral) compared to usual care or control in people undergoing gastrointestinal surgery
Population: people undergoing gastrointestinal surgery
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Non‐ infectious complications recorded up to 30 days postdischarge Immune‐enhancing supplements (oral or enteral) vs usual care or control | RR 0.79 [0.62, 1] | 8 studies · 1020 participants | Low Downgraded: risk of bias, imprecision |
Infectious complications recorded up to 30 days postdischarge Immune‐enhancing supplements (oral or enteral) vs usual care or control | RR 0.74 [0.53, 1.04] | 7 studies · 925 participants | Low Downgraded: risk of bias, imprecision |
Length of hospital stay (days) Immune‐enhancing supplements (oral or enteral) vs usual care or control | no estimate extracted | 6 studies · 688 participants | Low Downgraded: risk of bias, inconsistency |
Adverse effects Immune‐enhancing supplements (oral or enteral) vs usual care or control | no estimate extracted | 3 studies · 399 participants | Ungraded |
Oral nutritional supplements compared to usual care or control in people undergoing gastrointestinal surgery
Population: people undergoing gastrointestinal surgery
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Non‐infectious complications recorded up to 30 days postdischarge Oral nutritional supplements vs usual care or control | RR 0.9 [0.67, 1.2] | 5 studies · 473 participants | Low Downgraded: risk of bias, imprecision |
Infectious complications recorded up to 30 days postdischarge Oral nutritional supplements vs usual care or control | RR 0.88 [0.6, 1.27] | 5 studies · 473 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Length of hospital stay (days) Oral nutritional supplements vs usual care or control | no estimate extracted | 3 studies · 299 participants | Low Downgraded: risk of bias, imprecision |
Adverse effects Oral nutritional supplements vs usual care or control | no estimate extracted | 4 studies · 373 participants | Ungraded |
Comparison
Population: preoperative patients undergoing GI surgery
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Total complications | RR 0.67 | 548 participants | Moderate |
Infectious complications | RR 0.51 | 488 participants | Moderate |
length of stay number of days | no estimate extracted | 549 participants | Moderate |
Comparison
Population: Patients undergoing GI surgery
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Total complications | RR 1.17 [0.54, 2.55] | 263 participants | Moderate |
Infectious complications | RR 1.09 [0.83, 1.42] | 250 participants | Moderate |
length of hospital stay | no estimate extracted | 206 participants | Moderate |
Comparison
Population: GI surgical patients
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Total complications | RR 0.64 [0.46, 0.87] | 260 participants | Low |
Infectious complications | RR 0.94 [0.8, 1.1] | 226 participants | Low |
Comparison
Population: preoperative GI patients
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
total complications | no estimate extracted | 120 participants | Low |
Infectious complications | no estimate extracted | 120 participants | Low |