Cochrane · systematic review · CD008796

Physical exercise training interventions for children and young adults during and after treatment for childhood cancer

Braam, KI, van der Torre, P, Takken, T, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library

Childhood Cancer2 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
10
current version
GRADE rated
8
No studies
2
Included studies
NR
No studies 2 · 20%Ungraded 0 · 0%Very low 2 · 20%Low 5 · 50%Moderate 1 · 10%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Current version only

Physical exercise training compared to usual care for children and young adults during and after treatment for childhood cancer

Population: children and young adults during and after treatment for childhood cancer
CD008796.PUB3 (current) · 10 questions
OutcomeEffectEvidenceStatus / GRADE
9‐minute run‐walk test wheeled distance counter
Physical exercise training vs usual care
no estimate extracted2 studies · 68 participantsLow
Downgraded: risk of bias, imprecision
Timed up‐and‐down stairs test stopwatch
Physical exercise training vs usual care
no estimate extracted2 studies · 68 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Timed up‐and‐go time test stopwatch
Physical exercise training vs usual care
no estimate extracted1 study · 40 participantsLow
Downgraded: risk of bias, imprecision
Body composition outcomes
Physical exercise training vs usual care
no estimate extractedNRNo studies
Bone mineral density (total body) DXA scan
Physical exercise training vs usual care
no estimate extracted1 study · 51 participantsModerate
Downgraded: risk of bias, imprecision, inconsistency
BMI Quetelet Index
Physical exercise training vs usual care
no estimate extracted2 studies · 64 participantsLow
Downgraded: risk of bias, imprecision, inconsistency
Ankle dorsiflexion strength Hand‐held dynamometer
Physical exercise training vs usual care
no estimate extracted1 study · 28 participantsLow
Downgraded: risk of bias, imprecision, inconsistency
Health‐related quality of life PedsQL ‐ General questionnaire (
Physical exercise training vs usual care
no estimate extracted1 study · 28 participantsLow
Downgraded: risk of bias, imprecision, inconsistency
Fatigue
Physical exercise training vs usual care
no estimate extractedNRNo studies
General fatigue PedsQL ‐ Fatigue questionnaire (
Physical exercise training vs usual care
no estimate extracted1 study · 22 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency

Physical exercise training compared with usual care for children and young adults during and after treatment for childhood cancer

Population: children and young adults during and after treatment for childhood cancer
CD008796.PUB2 · 12 questions
OutcomeEffectEvidenceStatus / GRADE
Cardiorespiratory outcomes
Physical exercise training vs usual care
no estimate extractedNRNo studies
9‐minute run‐walk test wheeled distance counter
Physical exercise training vs usual care
no estimate extracted1 study · 28 participantsLow
Downgraded: imprecision
Timed up‐and‐down stairs test stopwatch
Physical exercise training vs usual care
no estimate extracted1 study · 28 participantsLow
Downgraded: imprecision
Body composition outcomes
Physical exercise training vs usual care
no estimate extractedNRNo studies
Bone mineral density DXA scan
Physical exercise training vs usual care
no estimate extracted1 study · 51 participantsLow
Downgraded: imprecision
Body mass index Quetlet Index
Physical exercise training vs usual care
no estimate extracted2 studies · 64 participantsVery low
Downgraded: risk of bias, imprecision
Muscle endurance/strength outcomes
Physical exercise training vs usual care
no estimate extractedNRNo studies
Ankle Dorsiflexion Strength Hand‐held dynamometer
Physical exercise training vs usual care
no estimate extracted1 study · 28 participantsLow
Downgraded: imprecision
Health‐related quality of life
Physical exercise training vs usual care
no estimate extractedNRNo studies
Health‐related quality of life PedsQl ‐ General questionnaire (version 3.0)
Physical exercise training vs usual care
no estimate extracted1 study · 28 participantsLow
Downgraded: imprecision
Fatigue
Physical exercise training vs usual care
no estimate extractedNRNo studies
General fatigue PedsQl ‐ fatigue questionnaire
Physical exercise training vs usual care
no estimate extracted1 study · 22 participantsLow
Downgraded: imprecision