Cochrane · systematic review · CD008712

Cognitive behavioural therapy plus standard care versus standard care plus other psychosocial treatments for people with schizophrenia

Jones, C, Hacker, D, Meaden, A, et al. · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library

Schizophrenia2 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 2 · 28.6%Low 5 · 71.4%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Current version only

CBT compared to ALL OTHER PSYCHOLOGICAL THERAPIES for schizophrenia

Population: people with schizophrenia
CD008712.PUB3 (current) · 7 questions
OutcomeEffectEvidenceStatus / GRADE
Global state: relapse
CBT vs ALL OTHER PSYCHOLOGICAL THERAPIES
RR 1.05 [0.85, 1.29]5 studies · 375 participantsLow
Downgraded: risk of bias
Global state: rehospitalisation*
CBT vs ALL OTHER PSYCHOLOGICAL THERAPIES
RR 0.96 [0.82, 1.14]8 studies · 943 participantsLow
Downgraded: risk of bias
Mental state: General ‐ clinically important change (no improvement)
CBT vs ALL OTHER PSYCHOLOGICAL THERAPIES
RR 0.82 [0.67, 1.01]4 studies · 249 participantsLow
Downgraded: risk of bias
Adverse effect/event: death ‐ any cause
CBT vs ALL OTHER PSYCHOLOGICAL THERAPIES
RR 1.57 [0.62, 3.98]6 studies · 627 participantsLow
Downgraded: risk of bias, imprecision, indirectness
Functioning ‐ average scores (Social Functioning Scale, high = good)
CBT vs ALL OTHER PSYCHOLOGICAL THERAPIES
no estimate extracted1 study · 65 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Quality of life: average scores (MSQOL, high = good, medium term)
CBT vs ALL OTHER PSYCHOLOGICAL THERAPIES
no estimate extracted1 study · 64 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Satisfaction with treatment ‐ leaving the study early for any reason
CBT vs ALL OTHER PSYCHOLOGICAL THERAPIES
RR 0.86 [0.75, 0.99]26 studies · 2392 participantsLow
Downgraded: risk of bias

Cognitive behavioural therapy compared with other psychosocial therapies for schizophrenia

Population: patients with schizophrenia
CD008712.PUB2 · 6 questions
OutcomeEffectEvidenceStatus / GRADE
Adverse effect/event: 2. Adverse effects ‐ any ‐ medium‐termonly
Cognitive behavioural therapy vs other psychosocial therapies
RR 2 [0.71, 5.64]1 study · 198 participantsVery low
Downgraded: risk of bias, imprecision, publication bias
Global state: 1. Relapse ‐ long‐term
Cognitive behavioural therapy vs other psychosocial therapies
RR 0.91 [0.63, 1.32]5 studies · 350 participantsLow
Downgraded: risk of bias, publication bias
Global state: 2. Rehospitalisation ‐ long‐term
Cognitive behavioural therapy vs other psychosocial therapies
RR 0.86 [0.62, 1.21]5 studies · 294 participantsLow
Downgraded: risk of bias, publication bias
Mental state: 1. General ‐ No important or reliable change ‐ long‐term
Cognitive behavioural therapy vs other psychosocial therapies
RR 0.84 [0.64, 1.09]4 studies · 244 participantsVery low
Downgraded: risk of bias, indirectness, publication bias
Social functioning: 1a. Average scores (Social Functioning Scale, high = good)
Cognitive behavioural therapy vs other psychosocial therapies
no estimate extracted1 study · 65 participantsVery low
Downgraded: risk of bias, indirectness, publication bias
Quality of life: Average score (EuroQOL, high = good) ‐ long‐termonly
Cognitive behavioural therapy vs other psychosocial therapies
no estimate extracted1 study · 37 participantsVery low
Downgraded: risk of bias, imprecision, publication bias