Cochrane · systematic review · CD008597
Antibiotic prophylaxis for preventing post solid organ transplant tuberculosis
Adamu, B, Abdu, A, Abba, AA, et al. · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library
Kidney and TransplantAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
3
current version
GRADE rated
3
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 1 · 33.3%Moderate 2 · 66.7%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Isoniazid versus no treatment for preventing post solid organ transplant tuberculosis
Population: kidney transplant recipients
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Tuberculosis Isoniazid vs no treatment | RR 0.35 [0.14, 0.89] | 3 studies · 558 participants | Moderate Downgraded: risk of bias |
INH hepatotoxicity Jaundice, elevated bilirubin, elevated liver enzymes Isoniazid vs no treatment | RR 1.59 [1.06, 2.4] | 3 studies · 558 participants | Moderate Downgraded: risk of bias |
All‐cause mortality Isoniazid vs no treatment | RR 1.39 [0.7, 2.78] | 3 studies · 558 participants | Low Downgraded: risk of bias |