Cochrane · systematic review · CD008545
Hepatitis B immunoglobulin during pregnancy for prevention of mother‐to‐child transmission of hepatitis B virus
Eke, AC, Eleje, GU, Eke, UA, et al. · Cochrane Database of Systematic Reviews · 2017 · Cochrane Library
Hepato-BiliaryAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
5
current version
GRADE rated
3
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 2 · 40%Very low 2 · 40%Low 1 · 20%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Hepatitis B immunoglobulin (HBIG) versus no intervention for prevention of mother‐to‐child transmission of hepatitis B virus
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
All‐cause mortality or other serous adverse events of the newborn Hepatitis B immunoglobulin (HBIG) vs no intervention | no estimate extracted | 0 studies · 1 participants | Ungraded |
All‐cause mortality or other serous adverse events of the mothers Hepatitis B immunoglobulin (HBIG) vs no intervention | no estimate extracted | 0 studies · 1 participants | Ungraded |
Newborn with HBsAg‐positive result Hepatitis B immunoglobulin (HBIG) vs no intervention | RR 0.3 [0.24, 0.38] | 29 studies · 5310 participants | Very low Downgraded: risk of bias, indirectness |
Newborn with HBeAg‐positive result Hepatitis B immunoglobulin (HBIG) vs no intervention | RR 0.68 [0.43, 1.05] | 7 studies · 1764 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Newborn with HBV‐DNA‐positive result Hepatitis B immunoglobulin (HBIG) vs no intervention | RR 0.25 [0.15, 0.42] | 16 studies · 2130 participants | Low Downgraded: risk of bias |