Cochrane · systematic review · CD008370
Somatostatin analogues for pancreatic surgery
Gurusamy, KS, Koti, R, Fusai, G, et al. · Cochrane Database of Systematic Reviews · 2013 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 3 · 42.9%Very low 4 · 57.1%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Current version onlySomatostatin analogues for pancreatic surgery
Population: people with pancreatic surgery
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Perioperative mortality | RR 0.8 [0.56, 1.16] | 18 studies · 2210 participants | Very low Downgraded: risk of bias |
Treatment withdrawal | RR 1.55 [0.56, 4.33] | 9 studies · 1220 participants | Very low Downgraded: risk of bias, publication bias |
Re‐operation | RR 1.06 [0.69, 1.63] | 7 studies · 687 participants | Very low Downgraded: risk of bias, inconsistency, publication bias |
Anastomotic leak | RR 0.81 [0.51, 1.27] | 9 studies · 1585 participants | Ungraded |
Pancreatic fistula (clinically significant) | RR 0.69 [0.38, 1.29] | 4 studies · 292 participants | Very low Downgraded: risk of bias, publication bias |
Infected abdominal collections | RR 0.93 [0.66, 1.32] | 13 studies · 1965 participants | Ungraded |
Shock | RR 1 [0.46, 2.15] | 4 studies · 812 participants | Ungraded |
Somatostatin analogues for pancreatic surgery
Population: patients with pancreatic surgery
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Perioperative mortality | RR 0.8 [0.56, 1.16] | 18 studies · 2210 participants | Very low Downgraded: risk of bias |
Treatment withdrawal | RR 1.55 [0.56, 4.33] | 9 studies · 1220 participants | Very low Downgraded: risk of bias, publication bias |
Re‐operation | RR 1.06 [0.69, 1.63] | 7 studies · 687 participants | Very low Downgraded: risk of bias, inconsistency, publication bias |
Anastomotic leak | RR 0.81 [0.51, 1.27] | 9 studies · 1585 participants | Ungraded |
Pancreatic fistula (clinically significant) | RR 0.69 [0.34, 1.41] | 3 studies · 247 participants | Very low Downgraded: risk of bias, publication bias |
Infected abdominal collections | RR 0.93 [0.66, 1.32] | 13 studies · 1965 participants | Ungraded |
Shock | RR 1 [0.46, 2.15] | 4 studies · 812 participants | Ungraded |