Cochrane · systematic review · CD008351

Airway clearance techniques for bronchiectasis

Lee, AL, Burge, AT, Holland, AE · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library

Airways2 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
5
No studies
2
Included studies
NR
No studies 2 · 28.6%Ungraded 0 · 0%Very low 0 · 0%Low 5 · 71.4%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Current version only

Airway clearance techniques for individuals with stable bronchiectasis

Population: individuals with stable bronchiectasis
CD008351.PUB3 (current) · 7 questions
OutcomeEffectEvidenceStatus / GRADE
Number of exacerbations of bronchiectasis Frequency of acute exacerbations of bronchiectasis
RR 0.71 [0.23, 2.25]1 study · 20 participantsLow
Downgraded: risk of bias, imprecision
Hospitalisations
no estimate extractedNRNo studies
Health‐related quality of life (disease‐specific) Scale from 0 to 100; lower score indicates better HRQoL. SGRQ total score consists of weighted scores from 3 domains
no estimate extracted1 study · 20 participantsLow
Downgraded: risk of bias, imprecision
Health‐related quality of life (cough‐specific) Leicester Cough Questionnaire Scale from 0 to 133; higher score indicates better HRQoL. Contains 19 questions from 3 domains on a Likert scale
no estimate extracted1 study · 20 participantsLow
Downgraded: risk of bias
Health‐related quality of life (health status) COPD Assessment Tool. Scale from 0 to 5; higher score indicates worse HRQoL Contains 10 questions with 5‐point Likert scale
no estimate extracted1 study · 30 participantsLow
Downgraded: risk of bias
Respiratory symptoms (symptoms) Breathlessness, Cough and Sputum Scale Scale from 0 to 12. Lower score indicates fewer symptoms
no estimate extracted1 study · 30 participantsLow
Downgraded: risk of bias
Adverse events (AEs)
no estimate extractedNRNo studies

Airway clearance techniques for individuals with stable bronchiectasis

Population: individuals with stable bronchiectasis
CD008351.PUB2 · 7 questions
OutcomeEffectEvidenceStatus / GRADE
Number of exacerbations of bronchiectasis Frequency of acute exacerbations of bronchiectasis
RR 0.71 [0.23, 2.25]1 study · 20 participantsLow
Downgraded: risk of bias, imprecision
Hospitalisations
no estimate extractedNRNo studies
Health‐related quality of life (disease‐specific) Health‐related quality of life (disease specific). Scale from: 0 to 100 lower score indicates better HRQoL. SGRQ total score consists of weighted scores from 3 domains
no estimate extracted1 study · 20 participantsLow
Downgraded: risk of bias, imprecision
Health‐related quality of life (cough‐specific) Leicester Cough Questionnaire. Scale from: 0 to 133. Higher score indicates better HRQOL. Contains 19 questions from 3 domains on a Likert scale
no estimate extracted1 study · 20 participantsLow
Downgraded: risk of bias, imprecision
Lung function
no estimate extractedNRNo studies
Symptoms
no estimate extractedNRNo studies
Adverse events (AE)
no estimate extractedNRNo studies