Cochrane · systematic review · CD008312
Strategies for improving adherence to antiepileptic drug treatment in people with epilepsy
Al-aqeel, S, Gershuni, O, Al-sabhan, J, et al. · Cochrane Database of Systematic Reviews · 2020 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 1 · 16.7%Moderate 4 · 66.7%High 1 · 16.7%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Current version onlySummary of findings table
Population: adults and children with epilepsy
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Effects on adherence (behavioural interventions) | no estimate extracted | 4 studies · 391 participants | Moderate Downgraded: risk of bias |
Effects on adherence (educational interventions) | no estimate extracted | 13 studies · 1938 participants | Moderate Downgraded: risk of bias |
Effects on adherence (mixed interventions) | no estimate extracted | 4 studies · 612 participants | High |
Seizure frequency and/or seizure severity Assessed by National Hospital Seizure Severity Scale (NHS3), seizure diary and self‐reporting | no estimate extracted | 11 studies · 2147 participants | Moderate Downgraded: risk of bias |
Self‐efficacy | no estimate extracted | 5 studies · 453 participants | Low Downgraded: risk of bias |
Quality of life | no estimate extracted | 6 studies · 1027 participants | Moderate Downgraded: risk of bias |
Summary of findings table
Population: adults and children with epilepsy
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Effects on adherence (behavioural interventions) | no estimate extracted | 2 studies · 89 participants | Moderate Downgraded: risk of bias |
Effects on adherence (educational interventions) | no estimate extracted | 8 studies · 1153 participants | Moderate Downgraded: risk of bias |
Effects on adherence (mixed interventions) | no estimate extracted | 3 studies · 522 participants | High |
Seizure frequency and seizure severity | no estimate extracted | 6 studies · 1293 participants | Moderate Downgraded: risk of bias |
Self‐efficacy | no estimate extracted | 4 studies · 358 participants | Low Downgraded: risk of bias |
Quality of life | no estimate extracted | 2 studies · 117 participants | High |