Cochrane · systematic review · CD008216
Autologous hematopoietic stem cell transplantation following high‐dose chemotherapy for nonrhabdomyosarcoma soft tissue sarcomas
Peinemann, F, Enk, H, Smith, LA · Cochrane Database of Systematic Reviews · 2017 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
3
No studies
3
Included studies
NR
No studies 3 · 50%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 3 · 50%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Current version onlyAutologous hematopoietic stem cell transplantation following high‐dose chemotherapy for nonrhabdomyosarcoma soft tissue sarcoma
Population: people with non‐rhabdomyosarcoma soft tissue sarcoma
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Overall survival | HR 1.26 [0.7, 2.29] | 1 study · 83 participants | High |
Treatment‐related mortality | no estimate extracted | 1 study · 83 participants | High |
Disease‐free survival | no estimate extracted | NR | No studies |
Progression‐free survival | HR 1.34 [0.81, 2.2] | 1 study · 83 participants | High |
Non‐hematologic toxicity grade 3 to 4 | no estimate extracted | NR | No studies |
Health‐related quality of life | no estimate extracted | NR | No studies |
Autologous hematopoietic stem cell transplantation following high‐dose chemotherapy for non‐rhabdomyosarcoma soft tissue sarcoma
Population: patients with non‐rhabdomyosarcoma soft tissue sarcoma
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Overall survival | HR 1.26 [0.7, 2.29] | 1 study · 83 participants | High |
Progression‐free survival | HR 1.34 [0.81, 2.2] | 1 study · 83 participants | High |
Treatment‐related mortality | no estimate extracted | 12 studies · 163 participants | Very low |
Health‐related quality of life | no estimate extracted | NR | No studies |
Disease‐free survival | no estimate extracted | 0 studies · 1 participants | Very low |
Non‐hematological toxicity grade 3 to 4 | no estimate extracted | 9 studies · 105 participants | Very low |
case series | no estimate extracted | 1 participants | Ungraded |