Cochrane · systematic review · CD008190

Appetite stimulants for people with cystic fibrosis

McTavish, D, Thornton, J · Cochrane Database of Systematic Reviews · 2022 · Cochrane Library

Cystic Fibrosis and Genetic Disorders2 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 7 · 100%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Current version only

Appetite stimulants versus placebo for people with cystic fibrosis

Population: people with cystic fibrosis
CD008190.PUB3 (current) · 7 questions
OutcomeEffectEvidenceStatus / GRADE
Change in weight (kg)
Appetite stimulants vs placebo
no estimate extracted2 studies · 42 participantsLow
Downgraded: risk of bias, imprecision
Change in weight (kg)
Appetite stimulants vs placebo
no estimate extracted1 study · 17 participantsLow
Downgraded: risk of bias, imprecision
Change in weight z score
Appetite stimulants vs placebo
no estimate extracted3 studies · 40 participantsLow
Downgraded: risk of bias, imprecision
Change in weight z score
Appetite stimulants vs placebo
no estimate extracted1 study · 17 participantsLow
Downgraded: risk of bias, imprecision
Change in FEV1 % predicted
Appetite stimulants vs placebo
no estimate extracted2 studies · 42 participantsLow
Downgraded: risk of bias, imprecision
Change in FEV1 % predicted
Appetite stimulants vs placebo
no estimate extracted1 study · 17 participantsLow
Downgraded: risk of bias, imprecision
Increase in appetite (subjective reporting)
Appetite stimulants vs placebo
OR 45.25 [3.57, 573.33]2 studies · 23 participantsLow
Downgraded: risk of bias, imprecision

Appetite stimulants versus placebo for people with cystic fibrosis

Population: people with cystic fibrosis
CD008190.PUB2 · 7 questions
OutcomeEffectEvidenceStatus / GRADE
Change in weight (kg) ‐ at 3 months
Appetite stimulants vs placebo
no estimate extracted1 study · 17 participantsModerate
Downgraded: risk of bias
Change in weight (kg) ‐ at 6 months
Appetite stimulants vs placebo
no estimate extracted1 study · 17 participantsModerate
Downgraded: risk of bias
Change in weight z score ‐ at 3 months
Appetite stimulants vs placebo
no estimate extracted3 studies · 40 participantsModerate
Downgraded: risk of bias
Change in weight z score ‐ at 6 months
Appetite stimulants vs placebo
no estimate extracted1 study · 17 participantsModerate
Downgraded: risk of bias
Change in FEV1 (% predicted) ‐ at 3 months
Appetite stimulants vs placebo
no estimate extracted1 study · 17 participantsModerate
Downgraded: risk of bias
Change in FEV1 (% predicted) ‐ at 6 months
Appetite stimulants vs placebo
no estimate extracted1 study · 17 participantsModerate
Downgraded: risk of bias
Increase in appetite (subjective reporting)
Appetite stimulants vs placebo
OR 45.25 [3.57, 573.33]2 studies · 23 participantsModerate
Downgraded: risk of bias