Cochrane · systematic review · CD008115
Systemic corticosteroids for acute sinusitis
Venekamp, RP, Thompson, MJ, Hayward, G, et al. · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 2 · 28.6%Moderate 5 · 71.4%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Current version onlyOral corticosteroids versus placebo or NSAID for acute sinusitis
Population: patients with acute sinusitis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Proportion of patients with resolution or improved symptoms at days 3 to 7 Oral corticosteroids vs placebo or NSAID | RR 1.33 [1.09, 1.62] | 5 studies · 1043 participants | Moderate Downgraded: risk of bias |
Proportion of patients with resolution or improved symptoms at days 3 to 7 ‐ Co‐treatment with antibiotics Oral corticosteroids vs placebo or NSAID | RR 1.4 [1.08, 1.81] | 4 studies · 869 participants | Low Downgraded: risk of bias |
Proportion of patients with resolution or improved symptoms at days 3 to 7 ‐ Corticosteroid monotherapy Oral corticosteroids vs placebo or NSAID | RR 1.12 [0.87, 1.44] | 1 study · 174 participants | Moderate Downgraded: imprecision |
Proportion of patients with resolution or improved symptoms at days 4 to 14 Oral corticosteroids vs placebo or NSAID | RR 1.23 [1.02, 1.49] | 5 studies · 1116 participants | Moderate Downgraded: risk of bias |
Proportion of patients with resolution or improved symptoms at days 4 to 14 ‐ Co‐treatment with antibiotics Oral corticosteroids vs placebo or NSAID | RR 1.32 [1.04, 1.68] | 4 studies · 945 participants | Low Downgraded: risk of bias |
Proportion of patients with resolution or improved symptoms at days 4 to 14 ‐ Corticosteroid monotherapy Oral corticosteroids vs placebo or NSAID | RR 0.99 [0.85, 1.16] | 1 study · 171 participants | Moderate Downgraded: imprecision |
Adverse events Oral corticosteroids vs placebo or NSAID | no estimate extracted | 5 studies · 1193 participants | Moderate |
Comparison
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Proportion of patients with resolution or improved symptoms at days 3 to 7 | RR 1.4 [1.08, 1.81] | 4 studies · 869 participants | Moderate |
Proportion of patients with resolution or improved symptoms at days 4 to 10 or 12 | RR 1.32 [1.04, 1.68] | 4 studies · 945 participants | Moderate |